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Naslov:Combination of lung ultrasound (a comet-tail sign) and N-terminal pro-brain natriuretic peptide in differentiating acute heart failure from chronic obstructive pulmonary disease and asthma as cause of acute dyspnea in prehospital emergency setting
Avtorji:ID Prosen, Gregor (Avtor)
ID Klemen, Petra (Avtor)
ID Strnad, Matej (Avtor)
ID Grmec, Štefek (Avtor)
Datoteke:.pdf Critical_Care_2011_Prosen_et_al._Combination_of_lung_ultrasound_(a_comet-tail_sign)_and_N-terminal_pro-brain_natriuretic_peptide_in_diff.pdf (420,76 KB)
MD5: A9152657A06A7BF9CB630E7278001024
 
URL http://ccforum.biomedcentral.com/articles/10.1186/cc10140
 
Jezik:Angleški jezik
Vrsta gradiva:Znanstveno delo
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:MF - Medicinska fakulteta
Opis:Introduction: We studied the diagnostic accuracy of bedside lung ultrasound (the presence of a comet tail sign), N-terminal pro-brain natriuretic peptide (NT-proBNP), and clinical assessment (modified Boston criteria) in differentiating heart failure (HF)- related acute dyspnea from pulmonary (COPD/asthma) related acute dyspnea in the prehospital setting. Methods: Prospective study was performed at the Center for Emergency Medicine Maribor, Slovenia, between July 2007 and April 2010. Two groups of patients were compared: HF-related acute dyspnea group (n = 129) vs pulmonary-related (asthma/COPD) acute dyspnea group (n = 89). All patients underwent lung ultrasound examination, along with basic laboratory, rapid NT-proBNP testing and chest X-ray. Results: Ultrasound comet tail sign has 100% sensitivity, 95% specificity, 100% negative predictive value (NPV) and 96% positive predictive value (PPV) for the diagnosis of HF. NT-proBNP (cut-off point 1000 pg/ml) has 92% sensitivity, 89% specificity, 86% NPV and 90% PPV. Boston modified criteria have 85% sensitivity, 86% specificity, 80% NPV and 90% PPV. Comparing the three methods, we found significant differences between ultrasound sign vs NT-proBNP (P<0.05) and Boston modified criteria (P<0.05). Combination of ultrasound sign and NT-proBNP has 100% sensitivity, 100% specificity, 100% NPV and 100% PPV. With ultrasound we can exclude HF in patients with pulmonary related dyspnea who have positive NT-proBNP (> 1000 pg/ml) and previous history of HF. Conclusions: Ultrasound comet tail sign alone or in combination with NT-proBNP has a high diagnostic accuracy in differentiating between acute HF and COPD/asthma causes of acute dyspnea in prehospital emergency setting.
Ključne besede:lungs, ultrasound, N-terminal pro-brain natriuretic peptide, acute heart failure, chronic obstructive pulmonary disease, asthma, acute dyspnea
Status publikacije:Objavljeno
Verzija publikacije:Objavljena publikacija
Leto izida:2011
Št. strani:str. 1-9
Številčenje:Letn. 15
PID:20.500.12556/DKUM-66511 Novo okno
ISSN:1466-609X
UDK:616.24-008.4-083.98
COBISS.SI-ID:3911231 Novo okno
DOI:10.1186/cc10140 Novo okno
ISSN pri članku:1466-609X
NUK URN:URN:SI:UM:DK:KXEEWJ6W
Datum objave v DKUM:29.06.2017
Število ogledov:2008
Število prenosov:402
Metapodatki:XML DC-XML DC-RDF
Področja:Ostalo
:
PROSEN, Gregor, KLEMEN, Petra, STRNAD, Matej in GRMEC, Štefek, 2011, Combination of lung ultrasound (a comet-tail sign) and N-terminal pro-brain natriuretic peptide in differentiating acute heart failure from chronic obstructive pulmonary disease and asthma as cause of acute dyspnea in prehospital emergency setting. Critical Care [na spletu]. 2011. Vol. 15, p. 1–9. [Dostopano 20 januar 2025]. DOI 10.1186/cc10140. Pridobljeno s: https://dk.um.si/IzpisGradiva.php?lang=slv&id=66511
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Gradivo je del revije

Naslov:Critical Care
Skrajšan naslov:Crit. Care
Založnik:BioMed Central
ISSN:1466-609X
COBISS.SI-ID:1137983 Novo okno

Licence

Licenca:CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
Povezava:http://creativecommons.org/licenses/by/4.0/deed.sl
Opis:To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
Začetek licenciranja:29.06.2017

Sekundarni jezik

Jezik:Slovenski jezik
Ključne besede:pljuča, ultrazvok, N-terminalni možganski natriuretični peptid, akutno srčno popuščanje, kronična obstruktivna pljučna bolezen, astma, akutna dispneja


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