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Naslov:Necrolytic migratory erythema associated with hyperglucagonemia and neuroendocrine hepatic tumors
Avtorji:ID Marko, Pij B. (Avtor)
ID Miljković, Jovan (Avtor)
ID Grmek-Zemljič, Tatjana (Avtor)
Datoteke:URL http://www.dlib.si/details/URN:NBN:SI:DOC-PN43NCWS
 
Jezik:Angleški jezik
Vrsta gradiva:Delo ni kategorizirano
Tipologija:1.02 - Pregledni znanstveni članek
Organizacija:UM - Univerza v Mariboru
Opis:We present a 61-year-old man with a 2-year history of persistent disseminated, psoriasiform annular pruritic lesions, acrodermatitis, weight loss, anemia and diabetes. Histopathology of the affected skin showed nonspecific subacute psoriasiform dermatitis. The computed tomographic scan of the abdomen revealed multiple hepatic tumors. Histopathological examination of ultrasound-guided needle biopsy from a hepatic lesion demonstrated a neuroendocrine tumor. Somatostatin-receptor scintigraphy with radio-labelled octreotide confirmed the likelihood of the neuroendocrine nature of the hepatic tumors and excluded the presence of other such lesions throughout the rest of the body, including the pancreas. The serum glucagon level was markedly increased. The diagnosis of necrolytic migratory erythema associated with hyperglucagonemia and neuroendocrine hepatic tumors was made and therapy with the long-acting somatostatin analogue octreotide was started. The skin changes resolved after the initiation of therapy, but no improvement of other symptoms was observed. Having reached the final stage of the disease, which was further complicated by congestive heart failure, the patient died one year later. As no autopsy was performed, we were unable to establish whether the hepatic tumors represented a metastatic process of previously undetected pancreatic glucagonoma or if they were extra-pancreatic glucagon-secreting tumors. The correct diagnosis of necrolytic migratory erythema is important, since it might be the clue for early detection of glucagonoma or of extra-pancreatic glucagon-secreting tumors.
Leto izida:2005
Št. strani:str. 161-164
Številčenje:Vol. 14, no. 4
PID:20.500.12556/DKUM-56165 Novo okno
UDK:616.5
COBISS.SI-ID:2170431 Novo okno
ISSN pri članku:1318-4458
NUK URN:URN:SI:UM:DK:D3EMQEAL
Datum objave v DKUM:21.12.2015
Število ogledov:1242
Število prenosov:34
Metapodatki:XML DC-XML DC-RDF
Področja:Ostalo
:
MARKO, Pij B., MILJKOVIĆ, Jovan in GRMEK-ZEMLJIČ, Tatjana, 2005, Necrolytic migratory erythema associated with hyperglucagonemia and neuroendocrine hepatic tumors. Acta dermatovenerologica Alpina, Panonnica et Adriatica [na spletu]. 2005. Vol. 14, no. 4, p. 161–164. [Dostopano 13 april 2025]. Pridobljeno s: http://www.dlib.si/details/URN:NBN:SI:DOC-PN43NCWS
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Gradivo je del revije

Naslov:Acta dermatovenerologica Alpina, Panonnica et Adriatica
Skrajšan naslov:Acta dermatovenerolog. Alp. Panon. Adriat.
Založnik:Slovene Welding Society
ISSN:1318-4458
COBISS.SI-ID:31649024 Novo okno

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