| Title: | Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum : an overview |
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| Authors: | ID Cör Andrejč, Darija (Author)
ID Knez, Željko (Author)
ID Knez Marevci, Maša (Author) |
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| Files: |  Antioxidant,_antibacterial,_antit-Andrejc-2022.pdf (1,26 MB)
MD5: 82973125D6DED6DB688E44FE50715F0D
 https://www.frontiersin.org/articles/10.3389/fphar.2022.934982/full
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| Language: | English |
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| Work type: | Scientific work |
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| Typology: | 1.02 - Review Article |
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| Organization: | FKKT - Faculty of Chemistry and Chemical Engineering
MF - Faculty of Medicine
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| Abstract: | Ganoderma lucidum is a very medicinal mushroom that has been utilized in Oriental medicine for many years. It has a wide range of pharmacological and therapeutic properties, and has been used for many years as a health promoter. It contains various biologically active compounds that improve the immune system and have antioxidant, antitumor, anti-inflammatory, antifungal, and antimicrobial properties. Active compounds include triterpenoids and polysaccharides, as well as proteins, lipids, phenolics, sterols, etc. In the following review, we summarize briefly their biological activities, such as antioxidant, anti-bacterial, anti-fungal, antitumor, anti-viral, and anti-inflammatory activity. Although Ganoderma has a number of medicinal effects that have been confirmed by the in vitro and in vivo studies summarised in this review, there are some limitations. Clinical trials face mainly a lack of pure constituents. Accurate identification of the compounds obtained is also problematic. In addition, most of the included studies were small, and there were concerns about the methodological quality of each study. Studies have shown that Ganoderma has valuable potential for the prevention and treatment of cancer. In any case, G. lucidum cannot be used as first-line therapy for cancer. |
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| Keywords: | Ganoderma lucidum, bioactive function, active compounds, polysaccharides, triterpenoids |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Submitted for review: | 03.05.2022 |
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| Article acceptance date: | 27.06.2022 |
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| Publication date: | 22.07.2022 |
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| Publisher: | Frontiers Media |
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| Year of publishing: | 2022 |
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| Number of pages: | 14 str. |
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| Numbering: | Vol. 13 |
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| PID: | 20.500.12556/DKUM-85014  |
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| UDC: | 577 |
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| ISSN on article: | 1663-9812 |
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| COBISS.SI-ID: | 116231939 |
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| DOI: | 10.3389/fphar.2022.934982 |
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| Copyright: | © 2022 Cör Andrejč, Knez and Knez
Marevci |
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| Publication date in DKUM: | 16.08.2023 |
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| Views: | 324 |
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| Downloads: | 55 |
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| Metadata: |    |
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| Categories: | Misc.
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CÖR ANDREJČ, Darija, KNEZ, Željko and KNEZ MAREVCI, Maša, 2022, Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum : an overview. Frontiers in pharmacology [online]. 2022. Vol. 13. [Accessed 13 April 2025]. DOI 10.3389/fphar.2022.934982. Retrieved from: https://dk.um.si/IzpisGradiva.php?lang=eng&id=85014
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