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Title:Nocebo učinek kot aktivacijski mehanizem potencirane akutne bolečine v zobozdravstveni ambulanti
Authors:ID Vozlič, Irena (Author)
ID Križmarić, Miljenko (Mentor) More about this mentor... New window
ID Pajnkihar, Majda (Comentor)
Files:.pdf MAG_Vozlic_Irena_2013.pdf (1,68 MB)
MD5: 9D290F3A81CB5DAEBE3E87DD6475F733
PID: 20.500.12556/dkum/87e86697-5e98-41e7-80d1-fa6be4ce08ea
 
Language:Slovenian
Work type:Master's thesis/paper
Typology:2.09 - Master's Thesis
Organization:FZV - Faculty of Health Sciences
Abstract:Posledice noceba so škodljivi, neprijetni ali neželeni učinki na organizem. Nocebo reakcije ljudje kemično ustvarimo zaradi pesimističnih prepričanj in pričakovanj. Če si mislimo, da nam lahko nekaj škoduje, obstaja visoka verjetnost, da nam bo tudi v resnici škodovalo. Raziskovalna metodologija: V krajši pilotski študiji na vzorcu 44 pacientov, ki je bila izvedena v zobozdravstveni ambulanti ob sanacijskem posegu, smo želeli raziskati, ali ima nocebo vpliv na stopnjo bolečine in vrednost pulza. Bolečino smo merili po VAS lestvici, pulz pa s pulznim oksimetrom. Podatke smo zajemali najprej pred posegom v ambulanti, nato med samim posegom sanacije, zatem pa je sledila aktivacija nocebo učinka, še preden je zobozdravnik zavrtal v živec. Rezultati: Rezultati so pokazali, da je mediana vrednost bolečine ob prihodu pacientov v ambulanto znašala 2 [IQR = 1–4, CI = 2–4], nato se je med pričetkom posega sanacije povišala na 5 [IQR = 3–6, CI = 4–6] (p < 0,001). Sledil je nocebo učinek in bolečina se je povečala na 8 [IQR = 6–9, CI = 6–8], kar je za 3 več v primerjavi s stanjem, ki bi bilo brez aktivacije noceba (p < 0,001). Podobno se je pulz iz začetne vrednosti v ambulanti 65 [IQR = 64–86, CI = 70–80] povečal na vrednost 81 [IQR = 72–91, CI = 76–88] (p < 0,001). Z nocebo učinkom smo ga še dodatno povečali na vrednost 92 [IQR = 78–103, CI = 85–97], (p < 0,001). Sklep: Z raziskavo smo pokazali, da je z nocebo mehanizmom mogoče aktivirati bolečino. Dokazali smo tudi povezavo med stopnjo bolečine in frekvenco pulza. Ugotovili smo, da moramo biti pri obravnavi pacientov izredno pazljivi, da z nocebo učinkom ne povzročamo bolečin do takšne mere, da bi jim škodovali.
Keywords:nocebo učinek, zobna gniloba, bolečina, pulz
Place of publishing:Maribor
Publisher:[I. Vozlič]
Year of publishing:2013
PID:20.500.12556/DKUM-40326 New window
UDC:616.314-616.8-009.7(043.2)
COBISS.SI-ID:1905060 New window
NUK URN:URN:SI:UM:DK:X6VS0H6E
Publication date in DKUM:30.05.2013
Views:2529
Downloads:232
Metadata:XML DC-XML DC-RDF
Categories:FZV
:
VOZLIČ, Irena, 2013, Nocebo učinek kot aktivacijski mehanizem potencirane akutne bolečine v zobozdravstveni ambulanti [online]. Master’s thesis. Maribor : I. Vozlič. [Accessed 10 April 2025]. Retrieved from: https://dk.um.si/IzpisGradiva.php?lang=eng&id=40326
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Secondary language

Language:English
Title:Activation nocebo mechanism effect potentiated acute pain in outpatuent dental clinicIC
Abstract:Consequences of nocebo are harmful, unpleasant or undesirable effects on the human body. Nocebo effects are chemical reactions which people generate due to pessimistic beliefs and expectations. If you think that something can do you harm, there is a high level of probability that the harm will actually be done. Research methodology: In a short pilot study of a 44-patient sample, conducted in the dental clinic at a remedial dental intervention, we wanted to investigate whether the nocebo effect increases the level of pain and the pulse values. The pain was measured by VAS scale, and the pulse by pulse oximetry. The data were taken in the clinic before the intervention, during the intervention and, finally, activation of the nocebo effect followed before drilling into the dental nerve. Results: The results showed that on arrival at the surgery the median pain was 2 [IQR = 1-4, CI = 2-4]. During the intervention it increased to 5 [IQR = 3-6, CI = 4-6] (p <0.001). After the nocebo effect the pain increased up to 8 [IQR = 6-9, CI = 6-8], which is by 3 more than without the nocebo activation (p <0.001). Similarly, the pulse increased from the initial value of 65 [IQR = 64-86, CI = 70-80] in the clinic to 81 [IQR = 72-91, CI = 76-88] (p <0.001). The nocebo effect further increased the value up to 92 [IQR = 78-103, CI = 85-97], (p <0.001). Conclusion: With this research we have shown, that pain can be activated with nocebo mechanism. We have to be very careful when we are using this mechanism, because we must not cause so much pain to patients, to hurt them.
Keywords:nocebo effect, tooth decay, pain, pulse


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