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Title:Use of AFM force spectroscopy for assessment of polymer response to conditions similar to the wound, during healing
Authors:ID Maver, Uroš (Author)
ID Maver, Tina (Author)
ID Žnidaršič, Andrej (Author)
ID Peršin Fratnik, Zdenka (Author)
ID Gaberšček, Miran (Author)
ID Stana-Kleinschek, Karin (Author)
ID Inštitut za kovinske materiale in tehnologije (Copyright holder)
Files:.pdf Materiali_in_Tehnologije_2011_Maver_et_al._Use_of_Afm_Force_Spectroscopy_for_Assessment_of_Polymer_Response_To_Conditions_Similar_To_the.pdf (316,48 KB)
MD5: 38C245A2A2E64255B1EC4D1D5B189246
PID: 20.500.12556/dkum/9dec9216-3d32-4bc8-9a01-b126e222c141
 
URL http://www.imt.si/Revija/izvodi/mit113/maver_U.htm
 
Language:English
Work type:Scientific work
Typology:1.01 - Original Scientific Article
Organization:FS - Faculty of Mechanical Engineering
Abstract:Force spectroscopy is a very promising technique for the evaluation of interactions within different environments. Knowledge about them is especially important during the design and preparation of those modern wound dressings in contact with a changing wound-environment over a prolonged time. Such exposure can cause a drastic decrease in the materialćs mechanical performance, and can lead to degradation, thus lowering the success of any healing process. Our study tries to establish a model system, which would enable us to assess the applicability of the mentioned technique for the evaluation of any interaction changes between polymer molecules and a chosen surface, after exposure to different environments. Our proposed experimental setup consists of two representative polymers, a model silicon surface, and two solutions of various pHs and ionic strengths, respectively. Within the chosen range of parameters, we are confident that we can prove the usefulness of force spectroscopy for further research into polymer suitability, for the development of novel wound dressings.
Keywords:force spectroscopy, AFM, wound dressings, polymer materials, model system
Publication status:Published
Publication version:Version of Record
Year of publishing:2011
Number of pages:str. 259-263
Numbering:Letn. 45, št. 3
PID:20.500.12556/DKUM-26820 New window
ISSN:1580-2949
UDC:533.53:678
ISSN on article:1580-2949
COBISS.SI-ID:14986262 New window
NUK URN:URN:SI:UM:DK:GTPPTYKU
Publication date in DKUM:01.06.2012
Views:2037
Downloads:110
Metadata:XML DC-XML DC-RDF
Categories:Misc.
:
MAVER, Uroš, MAVER, Tina, ŽNIDARŠIČ, Andrej, PERŠIN FRATNIK, Zdenka, GABERŠČEK, Miran and STANA-KLEINSCHEK, Karin, 2011, Use of AFM force spectroscopy for assessment of polymer response to conditions similar to the wound, during healing. Materiali in tehnologije [online]. 2011. Vol. 45, no. 3, p. 259–263. [Accessed 23 April 2025]. Retrieved from: https://dk.um.si/IzpisGradiva.php?lang=eng&id=26820
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Record is a part of a journal

Title:Materiali in tehnologije
Shortened title:Mater. tehnol.
Publisher:Inštitut za kovinske materiale in tehnologije
ISSN:1580-2949
COBISS.SI-ID:106193664 New window

Secondary language

Language:Slovenian
Title:Uporaba AFM-spektroskopije sil za spremljanje odziva polimernih molekul na v rani podobna okolja med celjenjem
Abstract:Spektroskopija sil je zelo obetavna tehnika za uporabo pri določanju interakcij v številnih različnih okoljih. Poznanje le-teh je še posebej pomembno pri načrtovanju in pripravi novodobnih obližev, ki morajo biti v stiku z rano dalj časa in so tako izpostavljeni spreminjajočemu se okolju. To lahko na samem materialu povzroči drastične spremembe in vodi v otežen potek celjenja. V tem delu smo želeli pripraviti modelni sistem, s katerim bi preverjali možnost uporabe omenjene tehnike za ugotavljanje sprememb interakcij med polimernimi molekulami ter izbrano površino po izpostavitvi različnim okoljem. Eksperimentalni sistem je vseboval dva vzorčna polimera, modelno silicijevo površino ter po dve raztopini z različnimi pH in ionskimi močmi. S takim naborom parametrov smo zajeli dovolj možnosti za ugotovitev uporabnosti tehnike za nadaljnje raziskave primernosti polimernih materialov za nove obliže.
Keywords:spektroskopija sil, mikroskopija na atomsko silo, obliži, polimerni materiali, modelni sistem


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