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Title:Akutna respiracijska acidoza in alkaloza : sodobna kvantitativna interpretacija
Authors:ID Stožer, Andraž (Author)
ID Rupnik, Marjan (Author)
Files:.pdf Zdravniski_vestnik_2014_Stozer,_Slak_Rupnik_Akutna_respiracijska_acidoza_in_alkaloza_-_Sodobna_kvantitativna_interpretacija.pdf (780,41 KB)
MD5: 56A8D2547B9E3BE0CCBDA277032DA760
 
URL http://vestnik.szd.si/index.php/ZdravVest/article/view/1100
 
Language:Slovenian
Work type:Scientific work
Typology:1.02 - Review Article
Organization:MF - Faculty of Medicine
Abstract:Izhodišče: Obstajajo trije različni pristopi k oceni kislinsko-baznega stanja bolnika: bostonski, kopenhagenski in Stewartov, ki temeljijo na različnih izmerjenih parametrih. Poleg vnetih debat o tem, kateri od pristopov je boljši, vnaša med študente, raziskovalce in klinike zmedo dejstvo, da med svojim študijem tipično osvojijo le enega od omenjenih pristopov in zato ne morejo v celoti razumeti virov, ki uporabljajo katerega od drugih pristopov, poleg tega pa ne morejo kritično oceniti prednosti in omejitev določenega pristopa. Avtorja v članku predstaviva in opredeliva osnovne parametre, značilne za posamezne pristope, in poudariva razlike in podobnosti med njimi. Posebno pozornost namenjava vprašanju, kako posamezni pristopi ocenjujejo spremembo v koncentraciji plazemskega bikarbonata, do katere pride med primarnimi respiracijskimi spremembami in katerih ustrezno razumevanje je potrebno za pravilno interpretiranje kroničnih respiracijskih in metaboličnih kislinsko-baznih sprememb. Zaključek: Med akutno respiracijsko acidozo se koncentracija bikarbonata zviša in med akutno respiracijsko alkalozo zniža v odvisnosti od moči nebikarbonatnih pufrov. Med akutnimi respiracijskimi motnjami se koncentracija pufrske baze (uporablja jo kopenhagenski pristop), navidezna razlika močnih ionov, efektivna razlika močnih ionov in vrzel močnih ionov (uporablja jih Stewartov pristop) ne spremenijo, anionska vrzel (uporabljata jo bostonski in kopenhagenski pristop) pa se med akutno respiracijsko acidozo zmanjša, med akutno respiracijsko alkalozo pa zveča.
Keywords:respiratorne motnje, Davenportov diagram, Gamblov diagram, kislinsko-bazna motnja
Publication status:Published
Publication version:Version of Record
Year of publishing:2014
Number of pages:str. 147-157
Numbering:Letn. 83, št. 2
PID:20.500.12556/DKUM-56836 New window
ISSN:1318-0347
UDC:616.152.11-07:612
ISSN on article:1318-0347
COBISS.SI-ID:512392248 New window
NUK URN:URN:SI:UM:DK:KXQ6QHR5
Publication date in DKUM:30.12.2015
Views:2682
Downloads:150
Metadata:XML DC-XML DC-RDF
Categories:Misc.
:
STOŽER, Andraž and RUPNIK, Marjan, 2014, Akutna respiracijska acidoza in alkaloza : sodobna kvantitativna interpretacija. Zdravniški vestnik. glasilo Slovenskega zdravniškega društva [online]. 2014. Vol. 83, no. 2, p. 147–157. [Accessed 6 April 2025]. Retrieved from: https://dk.um.si/IzpisGradiva.php?lang=eng&id=56836
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Record is a part of a journal

Title:Zdravniški vestnik. glasilo Slovenskega zdravniškega društva
Publisher:Slovensko zdravniško društvo
ISSN:1318-0347
COBISS.SI-ID:32893696 New window

Licences

License:CC BY-NC 4.0, Creative Commons Attribution-NonCommercial 4.0 International
Link:http://creativecommons.org/licenses/by-nc/4.0/
Description:A creative commons license that bans commercial use, but the users don’t have to license their derivative works on the same terms.
Licensing start date:30.12.2015

Secondary language

Language:English
Abstract:Background: Three different approaches for assessing the acid-base status of a patient exist, i.e. the Boston, Copenhagen, and Stewart's approach, and they employ different parameters to assess a given acid-base disturbance. Students, researchers, and clinicians are getting confused by heated debates about which of these performs best and by the fact that during their curricula, they typically get acquainted with one of the approaches only, which prevents them to understand sources employing other approaches and to critically evaluate the advantages and drawbacks of each approach. In this paper, the authors introduce and define the basic parameters characterizing each of the approaches and point out differences and similarities between them. Special attention is devoted to how the different approaches assess the degree of change in the concentration of plasma bicarbonate that occurs during primary respiratory changes; proper understanding of these is necessary to correctly interpret chronic respiratory and metabolic acidbase changes. Conclusion: During acute respiratory acidosis the concentration of bicarbonate rises and during acute respiratory alkalosis it falls, depending on the buffering strength of non-bicarbonate buffers. During acute respiratory acid-base disturbances, buffer base (employed by the Copenhagen approach), apparent and effective strong ion difference, as well as strong ion gap (employed by the Stewart approach) remain unchanged; the anion gap (employed by the Boston and Copenhagen approach) falls during acute respiratory acidosis and rises during acute respiratory alkalosis.
Keywords:Davenport, Gamble diagram, acid-base disturbance


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