| Title: | Synergistic effect of supercritical and ultrasound-assisted ginger (Zingiber officinale Roscoe) extracts |
|---|
| Authors: | ID Žitek Makoter, Taja (Author)
ID Kučuk, Nika (Author)
ID Postružnik, Vesna (Author)
ID Leitgeb, Maja (Author)
ID Knez, Željko (Author)
ID Primožič, Mateja (Author)
ID Knez Marevci, Maša (Author) |
|---|
| Files: |  plants-11-02872-v2.pdf (1,59 MB)
MD5: F7C38393EFB0BEE09CD029CD87F9BFD4
 https://www.mdpi.com/2223-7747/11/21/2872
|
|---|
| Language: | English |
|---|
| Work type: | Article |
|---|
| Typology: | 1.01 - Original Scientific Article |
|---|
| Organization: | FKKT - Faculty of Chemistry and Chemical Engineering
MF - Faculty of Medicine
|
|---|
| Abstract: | Proper processing of natural material is crucial to obtain an extract with high content of
biologically active components. Dried, grinded ginger roots were extracted by ultrasonic method
and supercritical extraction with CO2
. The aim of the study was to determine if a mixture of the two
types of extracts attained by different methods and solvents exhibits better bioavailability than each
extract itself. Therefore, both extracts were analytically evaluated and then mixed in a ratio of 1:1.
The supercritical extract (SCG extract) and the mixed extract (mixG extract) had high antioxidant
activity (78% and 73%) and total phenols (827 mg/g ext. and 1455 mg/g ext.), which is also consistent
with the levels of gingerol (303 mg/g ext. and 271 g/g ext.) and shogaol (111 mg/g ext. and 100 g/g
ext.) in the extracts. In comparison to both pure extracts higher levels of total phenols were found
in the extract mixG. This could be the reason for the significant inhibition of melanoma cells and
antimicrobial potential (against Staphylococcus aureus, Escherichia coli, and Candida albicans). The
combination of the extracts resulted in a significant increase in the inhibition of selected microbial
and melanoma cells WM-266-4 compared to the control. Cell viability decreased below 60% when
mixG extract was applied. Antimicrobial activity has been confirmed. |
|---|
| Keywords: | ginger, supercritical fluid extraction, ultrasound-assisted extraction, antimicrobial activity |
|---|
| Publication status: | Published |
|---|
| Publication version: | Version of Record |
|---|
| Submitted for review: | 05.10.2022 |
|---|
| Article acceptance date: | 24.10.2022 |
|---|
| Publication date: | 27.10.2022 |
|---|
| Publisher: | MDPI |
|---|
| Year of publishing: | 2022 |
|---|
| Number of pages: | 14 str. |
|---|
| Numbering: | Vol. 11, iss. 21 |
|---|
| PID: | 20.500.12556/DKUM-92749  |
|---|
| UDC: | 66.02 |
|---|
| ISSN on article: | 2223-7747 |
|---|
| COBISS.SI-ID: | 128508675 |
|---|
| DOI: | 10.3390/plants11212872 |
|---|
| Copyright: | © 2022 by the authors |
|---|
| Publication date in DKUM: | 09.05.2025 |
|---|
| Views: | 0 |
|---|
| Downloads: | 12 |
|---|
| Metadata: |    |
|---|
| Categories: | Misc.
|
|---|
|
:
|
Copy citation |
|---|
| | | | Average score: | (0 votes) |
|---|
| Your score: | Voting is allowed only for logged in users. |
|---|
| Share: |  |
|---|
Hover the mouse pointer over a document title to show the abstract or click
on the title to get all document metadata. |
