| Naslov: | Films based on TEMPO-oxidized chitosan nanoparticles: Obtaining and potential application as wound dressings |
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| Avtorji: | ID Korica, Matea (Avtor)
ID Mihajlovski, Katarina (Avtor)
ID Mohan, Tamilselvan (Avtor)
ID Kostić, Mirjana M. (Avtor) |
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| Datoteke: |  1-s2.0-S0008621524001824-main.pdf (4,92 MB)
MD5: C9DC6A8221B4020382DBC931A568D111
 https://www.sciencedirect.com/science/article/pii/S0008621524001824
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| Jezik: | Angleški jezik |
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| Vrsta gradiva: | Članek v reviji |
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| Tipologija: | 1.01 - Izvirni znanstveni članek |
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| Organizacija: | FS - Fakulteta za strojništvo
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| Opis: | A series of novel films based on TEMPO-oxidized chitosan nanoparticles were prepared by casting method.
Fourier transform infrared spectroscopy (FTIR) was employed to ascertain the chemical structure of TEMPOoxidized chitosan. The surface morphology of the TEMPO-oxidized chitosan nanoparticles was analyzed by
atomic force microscopy (AFM). The physicochemical (area density, thickness, iodine sorption, roughness),
functional (moisture sorption, liquid absorption capacity, weight loss upon contact with the liquid, and water
vapor transmission rate), antibacterial, and antioxidant properties of films based on TEMPO-oxidized chitosan
nanoparticles were also investigated. The physicochemical properties of the films varied widely: area density
ranged from 77.83 ± 0.06 to184.46 ± 0.05 mg/cm2
, thickness varied between 80.5 ± 1.6 and 200.5 ± 1.6 μm,
iodine sorption spanned from 333.7 ± 2.1 to166.4 ± 2.2 mg I2/g, and roughness ranged from 4.1 ± 0.2 to 5.6 ±
0.3 nm. Similarly, the functional properties also varied significantly: moisture sorption ranged from 4.76 ± 0.03
to 9.62 ± 0.11 %, liquid absorption capacity was between 129.04 ± 0.24 and 159.33 ± 0.73 % after 24 h, weight
loss upon contact with the liquid varied between 31.06 ± 0.35 and 45.88 ± 0.58 % after 24 h and water vapor
transmission rate ranged from 1220.10 ± 2.91to1407.77 ± 5.22 g/m2 day. Despite the wide variations in
physicochemical and functional properties, all films showed maximum bacterial reduction of Staphylococcus
aureus and Escherichia coli, although they exhibited low antioxidant activity. The results suggest that the films
could be effectively utilized as antibacterial wound dressings. |
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| Ključne besede: | TEMPO-oxidized chitosan nanoparticles, films, antibacterial activity, wound dressings |
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| Status publikacije: | Objavljeno |
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| Verzija publikacije: | Objavljena publikacija |
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| Poslano v recenzijo: | 27.06.2024 |
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| Datum sprejetja članka: | 30.06.2024 |
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| Datum objave: | 01.07.2024 |
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| Založnik: | Elsevier |
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| Leto izida: | 2024 |
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| Št. strani: | 13 str. |
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| Številčenje: | Vol. 542, [article no.] 109203 |
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| PID: | 20.500.12556/DKUM-90630  |
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| UDK: | 579.222:620.3 |
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| COBISS.SI-ID: | 207177475 |
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| DOI: | 10.1016/j.carres.2024.109203 |
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| ISSN pri članku: | 1873-426X |
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| Datum objave v DKUM: | 11.09.2024 |
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| Število ogledov: | 56 |
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| Število prenosov: | 23 |
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| Metapodatki: |    |
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| Področja: | Ostalo
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