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Title:The synthesis, surface analysis, and cellular response of titania and titanium oxynitride nanotube arrays prepared on TiAl6V4 for potential biomedical applications
Authors:ID Kravanja, Katja Andrina (Author)
ID Suhadolnik, Luka (Author)
ID Bele, Marjan (Author)
ID Maver, Uroš (Author)
ID Rožanc, Jan (Author)
ID Knez, Željko (Author)
ID Knez Marevci, Maša (Author)
ID Finšgar, Matjaž (Author)
Files:.pdf 1-s2.0-S2238785423007147-main.pdf (8,31 MB)
MD5: E052EA33AF66C6F685979FB62E7147D2
URL https://www.sciencedirect.com/science/article/pii/S2238785423007147?via%3Dihub
Work type:Article
Typology:1.01 - Original Scientific Article
Organization:FKKT - Faculty of Chemistry and Chemical Engineering
MF - Faculty of Medicine
Abstract:Titania nanotubes are gaining prominence in the biomedical field as implant materials due to their mechanical durability, nano-rough properties, and positive influence on cellular response. This work aimed to synthesize titania and titanium oxynitride (TieOeN) nano- tubular arrays on TiAl6V4 substrates using an anodic oxidation process followed by annealing in air or by additional nitridation in NH3 atmosphere. Different nanotubular layers of unique morphology and structure were fabricated and investigated using advanced surface analysis and biocompatibility tests. In-depth surface analysis was per- formed by field emission scanning electron microscopy (FE-SEM), atomic force microscopy (AFM), 3D profilometry, X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and time-of-flight secondary ion mass spectroscopy (ToF-SIMS). Cell testing using adipose- derived mesenchymal stem cells and human fetal osteoblasts demonstrated good cell viability, high proliferative capacity, and a favorable overall effect on cell morphology for the TieOeN nanotubes.
Keywords:surface analysis, XPS, AFM, tandem ToF-SIMS, titania nanotubes, Ti-O-N nanotubes, anodization
Publication status:Published
Publication version:Version of Record
Submitted for review:28.01.2023
Article acceptance date:04.04.2023
Publication date:09.04.2023
Publisher:Brazilian Metallurgical Materials and Mining Association, Elsevier
Year of publishing:2023
Number of pages:str. 4074-4090
Numbering:Vol. 24
PID:20.500.12556/DKUM-88499 New window
ISSN on article:2214-0697
COBISS.SI-ID:151362051 New window
DOI:10.1016/j.jmrt.2023.04.021 New window
Publication date in DKUM:07.05.2024
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Record is a part of a journal

Title:Journal of materials research and technology
Publisher:Brazilian Metallurgical Materials and Mining Association, Elsevier
COBISS.SI-ID:56382211 New window

Document is financed by a project

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:P2-0046-2019
Name:Separacijski procesi in produktna tehnika

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:P2-0084-2020
Name:Nanostrukturni materiali

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:P3-0036-2022
Name:Bio-psiho-socialni model kvalitete življenja

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:P2-0393-2022
Name:Napredni materiali za nizkoogljično in trajnostno družbo

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:P2-0118-2022
Name:Tekstilna kemija in napredni tekstilni materiali

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:J1-2470-2020
Name:Biofunkcionalizacija 3D-tiskanih kovinskih zlitin kot novo nastajajoča strategija za zmanjšanje neželenih učinkov ortopedskih vsadkov

Funder:ARIS - Slovenian Research and Innovation Agency
Project number:J3-2538-2020
Name:Strategija za izboljšanje kvalitete življenja in ortopedskega zdravljenja hrustančnih poškodb - Napredni 3D (bio)tiskani nosilci za tkivno regeneracijo

Funder:Other - Other funder or multiple funders
Funding programme:Ministry of Education, Science, and Sport of the Republic of Slovenia

Funder:EC - European Commission
Funding programme:European Regional Development Fund (European Union)


License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.


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