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Title:Optimizacija postopka ekstrakcije učinkovin iz arnike arnica montana in formulacija produktov : master's thesis
Authors:ID Pequeno Alonso, Álvaro (Author)
ID Knez Marevci, Maša (Mentor) More about this mentor... New window
ID Knez, Željko (Co-mentor)
Files:.pdf MAG_Pequeno_Alonso_Alvaro_2022.pdf (2,03 MB)
MD5: FC212F847FF6DDE6DA3999DC6571D197
PID: 20.500.12556/dkum/2b728591-6b7d-4cbb-a4cd-47c5d4cf3886
 
Language:English
Work type:Master's thesis/paper
Typology:2.09 - Master's Thesis
Organization:FKKT - Faculty of Chemistry and Chemical Engineering
Abstract:Arnica Montana je obetaven vir bioaktivnih spojin, predvsem fenolov, ki zaradi svoje antioksidativne aktivnosti izkazujejo koristi za zdravje ljudi. Da bi dosegli stopnjo farmacevtske uporabe, je treba cvetove Arnice Montana predelati v izdelek, ki je primeren za preživetje. V ta namen so bile izvedene različne ekstrakcijske tehnike z različnimi topili: hladna maceracija, ultrazvok, Soxhlet in superkritični CO2; uporabljena topila so bila etanol, metanol in mešanica etanola in vode 95:5 (v:v). Analiza, ki je vključevala ultravijolično/vidno spektrometrijo, je bila opravljena za merjenje antioksidativne aktivnosti in celotne vsebnosti fenolov v ekstraktih. Končno je bil organogel oblikovan z uporabo izvlečka, olja konoplje in voska riževih otrobov ter testiran glede njegove stabilnosti. V okviru tega dela je bil prvič formuliran organogel z visoko stabilnostjo, saj do sedaj v znanstveni literaturi ni bilo podatkov o tovrstni formulaciji. Za določitev njegovih reoloških lastnosti in topnosti v različnih topilih pri različnih temperaturnih pogojih bodo potrebne dodatne študije.
Keywords:Arnica Montana, organogels, solvent extraction, phenolic compounds, isolation, formulation
Place of publishing:Maribor
Place of performance:Maribor
Publisher:[A. Pequeno Alonso]
Year of publishing:2022
Number of pages:1 spletni vir (1 datoteka PDF (44 f.))
PID:20.500.12556/DKUM-82010 New window
UDC:66.061.3:633.88(043.2)
COBISS.SI-ID:116232963 New window
Publication date in DKUM:13.07.2022
Views:420
Downloads:31
Metadata:XML RDF-CHPDL DC-XML DC-RDF
Categories:KTFMB - FKKT
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Licences

License:CC BY 4.0, Creative Commons Attribution 4.0 International
Link:http://creativecommons.org/licenses/by/4.0/
Description:This is the standard Creative Commons license that gives others maximum freedom to do what they want with the work as long as they credit the author.
Licensing start date:28.06.2022

Secondary language

Language:Slovenian
Title:Optimization of extraction of active compounds from arnica montana and product formulation
Abstract:Arnica Montana is a promising source of bioactive compounds, mainly phenols, which, due to their antioxidant activity, show health benefits in humans. To reach a stage of pharmaceutical use, Arnica Montana flowers need to be processed into a viable product. For this purpose, various extractions techniques with different solvents were performed: cold maceration, ultrasounds, Soxhlet, and supercritical CO2; the solvents used were ethanol, methanol, and a 95:5 (v:v) mixture of ethanol and water. Analysis involving ultraviolet/visible spectrometry were accomplished to measure the antioxidant activity and the total phenolic content of the extracts. Finally, an organogel was formulated using the extract, cannabis oil, and rice bran wax and was tested for its stability. In the frame of this work, organogel with a high stability has been formulated for the first time, since until now, scientific literature does not provide any data of such kind of formulation. Additional studies will be required to determine its rheologic properties and solubility in different solvents at various temperature conditions.
Keywords:Arnica Montana, organogels, solvent extraction, phenolic compounds, supercritical fluid extraction


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