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Title:Antigenotoksični potencial rožmarinskih ekstraktov : magistrsko delo
Authors:ID Lečnik, Katja (Author)
ID Bren, Urban (Mentor) More about this mentor... New window
ID Žegura, Bojana (Co-mentor)
Files:.pdf MAG_Lecnik_Katja_2022.pdf (2,10 MB)
MD5: 852F3CB9260BF255A0D70B3E4CFBE40C
PID: 20.500.12556/dkum/b69bb4a9-7809-47fd-801f-4045c06f4a21
Work type:Master's thesis/paper
Typology:2.09 - Master's Thesis
Organization:FKKT - Faculty of Chemistry and Chemical Engineering
Abstract:V magistrski nalogi smo preučevali delovanje rožmarinskih ekstraktov (1 % in 2 %) na človeške celice in poskušali pokazati, da rožmarin deluje antigenotoksično in antioksidativno. V raziskavi smo uporabili celice človeškega hepatocelularnega hepatoma (HepG2). S pomočjo testa MTT smo preučevali citotoksičnost samih ekstraktov, s testom komet pa morebitne poškodbe DNK po izpostavitvi celic proučevanim spojinam v kombinaciji s tert-butil hidroksidom (t-BHP) in aflatoksinom B1 (AFB1).
Keywords:rožmarinski ekstrakt, rožmarinska kislina, AFB1, t-BHP, antioksidant, antigenotoksičen, test MTT, test komet, HepG2
Place of publishing:Maribor
Place of performance:Maribor
Publisher:[K. Lečnik]
Year of publishing:2022
Number of pages:1 spletni vir (1 datoteka PDF (VII, 34 f.))
PID:20.500.12556/DKUM-81447 New window
COBISS.SI-ID:106736131 New window
Publication date in DKUM:03.05.2022
Categories:KTFMB - FKKT
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License:CC BY-NC-ND 4.0, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Description:The most restrictive Creative Commons license. This only allows people to download and share the work for no commercial gain and for no other purposes.
Licensing start date:27.03.2022

Secondary language

Title:Antigenotoxic potential of rosemary extracts
Abstract:In the Master thesis we studied the effect of rosemary extracts (1 % and 2 %) on human cells and tried to show that rosemary exhibits antigenotoxic and antioxidant effects. Human hepatocellular hepatoma cells (HepG2) were used in the studies. Using the MTT test, we studied the cytotoxicity of the extracts themselves, with the comet test we tested a possible DNA cell damage after treatment with the studied compounds in combination with tert-butyl hydroxide (t-BHP) and aflatoxin B1 (AFB1).
Keywords:rosemary extract, rosemary acid, AFB1, t-BHP, antioxidant, antigenotoxic, MTT test, comet test, HepG2


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