| | SLO | ENG | Cookies and privacy

Bigger font | Smaller font

Show document

Title:Highly divergent Clostridium difficile strains isolated from the environment
Authors:Janežič, Sandra (Author)
Potočnik, Mojca (Author)
Tkalec, Valerija (Author)
Rupnik, Maja (Author)
Files:.pdf PLOS_ONE_2016_Janezic_et_al._Highly_Divergent_Clostridium_difficile_Strains_Isolated_from_the_Environment.pdf (1,13 MB)
URL http://dx.plos.org/10.1371/journal.pone.0167101
Work type:Scientific work (r2)
Typology:1.01 - Original Scientific Article
Organization:MF - Faculty of Medicine
Abstract:Clostridium difficile is one of the most important human and animal pathogens. However, the bacterium is ubiquitous and can be isolated from various sources. Here we report the prevalence and characterization of C. difficile in less studied environmental samples, puddle water (n = 104) and soil (n = 79). C. difficile was detected in 14.4% of puddle water and in 36.7% of soil samples. Environmental strains displayed antimicrobial resistance patterns comparable to already published data of human and animal isolates. A total of 480 isolates were grouped into 34 different PCR ribotypes. More than half of these (52.9%; 18 of 34) were already described in humans or animals. However, 14 PCR ribotypes were new in our PCR ribotype library and all but one were non-toxigenic. The multilocus sequence analysis of these new PCR ribotypes revealed that non-toxigenic environmental isolates are phylogenetically distinct and belong to three highly divergent clades, two of which have not been described before. Our data suggest that environment is a potential reservoir of genetically diverse population of C. difficile.
Keywords:clostridium difficile, environment, isolation
Year of publishing:2016
Number of pages:str. 1-12
Numbering:št. 11, Letn. 11
ISSN on article:1932-6203
COBISS_ID:512659256 Link is opened in a new window
DOI:10.1371/journal.pone.0167101 Link is opened in a new window
License:CC BY 4.0
This work is available under this license: Creative Commons Attribution 4.0 International
Average score:(0 votes)
Your score:Voting is allowed only for logged in users.
AddThis uses cookies that require your consent. Edit consent...

Hover the mouse pointer over a document title to show the abstract or click on the title to get all document metadata.

Record is a part of a journal

Title:PloS ONE
Publisher:Public Library of Science
COBISS.SI-ID:2005896 New window

Document is financed by a project

Funder:ARRS - Agencija za raziskovalno dejavnost Republike Slovenije (ARRS)
Project no.:J3-4298
Name:Vloga okolja in gostitelja pri pojavu in razvoju okužbe s Clostridium difficile

Secondary language

Keywords:clostridium difficile, okolje, izolacija


Leave comment

You have to log in to leave a comment.

Comments (0)
0 - 0 / 0
There are no comments!

Logos of partners University of Maribor University of Ljubljana University of Primorska University of Nova Gorica