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Title:Zastrupitve s plini
Authors:ID Sinkovič, Andreja (Author)
Files:URL http://www.dlib.si/details/URN:NBN:SI:DOC-OYVYN3UO
 
Language:Slovenian
Work type:Not categorized (r6)
Typology:1.02 - Review Article
Organization:UM - University of Maribor
Abstract:Le 5,5 % vseh zastrupitev je posledica zastrupitve z vdihavanjem strupenih snovi (plinov, hlapov, par ali aerosolov), največ zaradi dražečih ali dušljivih plinov. Po resorpciji skozi dihala se v telesu metabolizirajo pod vplivom metabolnih procesov. Izločijo se z izdihanim zrakom skozi pljuča (ogljikov monoksid, cianidi, vodikov sulfid) ali v spremenjeni obliki s sečem ali blatom. Enostavni dušljivci (ogljikov dioksid) povzročajo v visokih koncentracijah anoksično, kemični dušljivci (ogljikov monoksid, žveplovodik, cianidi) pa tkivno hipoksijo. Največ smrtnih primerov je zaradi akutne zastrupitve z ogljikovim monoksidom, ki lahko povzroča tudi pozne nevrološke okvare. Dražeči vodotopni ali v maščobah topni plini dražijo sluznice dihal in so pogosto vzrok akutnih in kroničnih zastrupitev v industriji, gospodinjstvih in prometu. Ob lokalnem draženju (kašelj, hripavost, težka sapa, traheobronhitis, edem glasilk, akutna zapora zgornjih dihal, kemični pnevmonitis, toksični pljučni edem) povzročajo tudi sistemske učinke, kot so glavobol, slabost, bruhanje, zmedenost, omotičnost, v hudih primerih celo nezavest, zastoj dihanja in prekatne, življenje ogrožajoče aritmije. Pri oskrbi bolnika je prvi ukrep odstranitev zastrupljenca s kontaminiranega področja, nato vzdrževanje življenjskih funkcij, vključno z dajanjem kisika, protistrupa in simptomatskim zdravljenjem.
Year of publishing:2009
Number of pages:str. 69-76
Numbering:Letn. 48, št. 1/2
PID:20.500.12556/DKUM-56158 New window
UDC:615.9
ISSN on article:0025-8121
COBISS.SI-ID:3297855 New window
NUK URN:URN:SI:UM:DK:MAH7JWLD
Publication date in DKUM:21.12.2015
Views:2014
Downloads:98
Metadata:XML RDF-CHPDL DC-XML DC-RDF
Categories:Misc.
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Record is a part of a journal

Title:Medicinski razgledi
Shortened title:Med. razgl.
Publisher:Medicinski razgledi
ISSN:0025-8121
COBISS.SI-ID:3390978 New window

Secondary language

Language:English
Title:Gas poisoning
Abstract:5.5% of all intoxications occur as a consequence of inhaling a toxic substance (gases, fumes, vapours or aerosols), in particular asphyxiant and irritant gases. Gases are absorbed through the lungs and are metabolized or biochemically transformed in the body under the influence of various enzymatic processes. They are excreted by the lungs (carbon monoxide, cyanides,hydrogen sulphide) or through the kidney and stool. Simple asphyxiants (carbon dioxide) cause anoxic hypoxia in high concentrations, whereas chemical asphyxiants (carbon monoxide, hydrogen sulfide, cyanides) cause tissue hypoxia. Most of the lethal cases are the consequence of acute carbon monoxide poisoning, which can also result in late neurological sequelae. Water- or less water-soluble irritant gases primarily irritate the mucous membranes of the upper respiratory tract and are a frequent cause of acute and chronic poisonings in industry, households and traffic. In addition to local irritant effect such as cough, hoarseness, dyspnea, tracheobronchitis, glottis edema, acute upper airway obstruction, chemical pneumonitis and toxic pulmonary edema, they can also cause systemic effects such as headache, nausea, vomiting, confusion and dizziness, and in severe cases even respiratory arrest and life-threatening ventricular arrhythmia. In all gas poisonings, removal of the victim from the contaminated area is the first measure, followed by basic and advanced life support, including oxygen therapy, and the administration of antidotes and symptomatic therapy.


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