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Title:SINTEZA IN UPORABA ORGANSKIH BIORAZGRADLJIVIH AEROGELOV KOT NOSILCEV AKTIVNIH UČINKOVIN
Authors:Fajfar, Tanja (Author)
Novak, Zoran (Mentor) More about this mentor... New window
Knez, Željko (Co-mentor)
Files:.pdf UNI_Fajfar_Tanja_2010.pdf (9,31 MB)
MD5: 55AF2A708AEA2F1E79256F26510E7185
 
Language:Slovenian
Work type:Undergraduate thesis (m5)
Organization:FKKT - Faculty of Chemistry and Chemical Engineering
Abstract:Naravni polimeri so se uveljavili kot obetaven material za sintezo in pripravo nanoporoznih delcev. Eden izmed najbolj raziskanih in uporabljenih naravnih polimerov je alginat, ki ga pridobivajo iz različnih vrst rjavih morskih alg. Zaradi sposobnosti geliranja in nabrekanja ter nekaterih drugih lastnosti je zelo primeren kot nosilec aktivnih učinkovin. V diplomski nalogi smo pripravili 1,5%; 2% in 2,5% alginatne gele: monolite, ki smo jih narezali na koščke in sferične alginatne kroglice, v katere smo vezali nikotinsko kislino kot aktivno substanco. Nato smo jih superkritično posušili s CO2 in tako dobili organske biorazgradljive aerogele.
Keywords:alginat, aerogeli, nikotinska kislina, škrob, superkritično sušenje, nadzorovano sproščanje.
Year of publishing:2010
Publisher:[T. Fajfar]
Source:Maribor
UDC:544.774.2-961(043.2)
COBISS_ID:14995990 New window
NUK URN:URN:SI:UM:DK:DW062KHQ
Views:2251
Downloads:281
Metadata:XML RDF-CHPDL DC-XML DC-RDF
Categories:KTFMB - FKKT
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Secondary language

Language:English
Title:SYNTHESIS AND APPLICATION OF BIODEGRADABLE ORGANIC AEROGELS AS DRUG CARRIERS
Abstract:Natural polymers have established themselves as a promising material for the synthesis and preparation of nanoporous particles. One of the most researched and used natural polymers is alginate, which is obtained from different types of brown seaweed. Due to its ability to gel and swell and some other properties, alginate is very suitable as a carrier for active ingredients. In this thesis, we prepared 1.5%, 2% and 2.5% alginate gels: monoliths, which were cut into small pieces and spherical alginate beads, in which we introduce nicotinic acid as active substance. We then dried by supercritical CO2 and thus obtained biodegradable organic aerogels.
Keywords:alginate, aerogels, nicotinic acid, starch, supercritical drying, controlled release.


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