| | SLO | ENG | Cookies and privacy

Bigger font | Smaller font

Search the digital library catalog Help

Query: search in
search in
search in
search in
* old and bologna study programme


1 - 4 / 4
First pagePrevious page1Next pageLast page
Translational and personalized medicine
Krešimir Pavelić, Tamara Martinović, Sandra Kraljević-Pavelić, 2015, original scientific article

Abstract: The idea behind personalized medicine is to tailor health care to an individual’s unique genetic makeup. Hitherto, “one size fits all” approach was used in medicine. With the rise of personal medicine, we are moving towards a more precise, predictable and powerful medicine that is customized for each individual patient. To allow for an improvement in the acceleration and efficacy of drug development, high-throughput methods (“omics”) are rapidly being developed. This leads to understanding of multiple factors that are involved in disease progress on an individual level. In order to analyze the great amount of data that is collected from such experiments, one has to turn to systems biology, an interdisciplinary science that studies complex interactions within a biological system. Finally, translational medicine comes into play, by “translating” the information gathered from research into diagnostic tools, medicines and policies, with the final goal of improving individuals’ health. Personalized medicine is one of the future, and it will revolutionize the current practice of diagnosis-based medicine, once fully developed.
Keywords: personalized medicine, translational medicine, clinic, high-throughput methods, systems biology
Published: 08.10.2018; Views: 394; Downloads: 264
.pdf Full text (324,18 KB)
This document has many files! More...

Container throughput forecasting using dynamic factor analysis and ARIMAX model
Marko Intihar, Tomaž Kramberger, Dejan Dragan, 2017, original scientific article

Abstract: The paper examines the impact of integration of macroeconomic indicators on the accuracy of container throughput time series forecasting model. For this purpose, a Dynamic factor analysis and AutoRegressive Integrated Moving-Average model with eXogenous inputs (ARIMAX) are used. Both methodologies are integrated into a novel four-stage heuristic procedure. Firstly, dynamic factors are extracted from external macroeconomic indicators influencing the observed throughput. Secondly, the family of ARIMAX models of different orders is generated based on the derived factors. In the third stage, the diagnostic and goodness-of-fit testing is applied, which includes statistical criteria such as fit performance, information criteria, and parsimony. Finally, the best model is heuristically selected and tested on the real data of the Port of Koper. The results show that by applying macroeconomic indicators into the forecasting model, more accurate future throughput forecasts can be achieved. The model is also used to produce future forecasts for the next four years indicating a more oscillatory behaviour in (2018-2020). Hence, care must be taken concerning any bigger investment decisions initiated from the management side. It is believed that the proposed model might be a useful reinforcement of the existing forecasting module in the observed port.
Keywords: container throughput forecasting, ARIMAX model, dynamic factor analysis, exogenous macroeconomic indicators, time series analysis
Published: 12.12.2017; Views: 930; Downloads: 294
.pdf Full text (1,33 MB)
This document has many files! More...

Reduction of the roundabout capacity due to a strong stream of pedestrians and/or cyclists
Tomaž Tollazzi, 1999, original scientific article

Abstract: Single-lane roundabouts may face the problems of getting crowded and empty in their circulatory roadway due to a strong stream of pedestrians and/or cyclists. Vehicles at the roundabout entries or exits have to provide the right of way over pedestrians and/or cyclists. Therefore, it comes to disturbances and traffic jams. If there are jams at the entry carriageway, vehicles are unable to get into roundabouts. If there are jams at the exit carriageway, vehicles are not able to leave the roundabout. When the length of vehicle platoon at the exits so long that it reaches the preceding entry, the roundabouts suffer from getting fully overcrowded. The paper presents the methodology of calculating the reduction of the roundabout capacity due to the pedestrian or cyclist stream. The method of calculating the reduction of the roundabout capacity with the disturbed streams may be used for roundabouts in urban environments, where the strength of the cyclist or pedestrian streams is not negligible.
Keywords: road traffic, roundabouts, roundabout capacity, traffic throughput, bicyclists, pedestrians
Published: 05.06.2017; Views: 755; Downloads: 75
.pdf Full text (1,66 MB)
This document has many files! More...

Search done in 0.06 sec.
Back to top
Logos of partners University of Maribor University of Ljubljana University of Primorska University of Nova Gorica