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Opis: The study aimed to analyze whether the high compression of unique, tight-fitting sportswear influences the clothing physiology comfort of the athlete. Three specific sportswear with different compression were tested on four subjects while they were running on a treadmill with increasing intensity. The compression effect of the sportswear on the body of the test persons, the temperature distribution of the subjects, and the intensity of their perspiration during running were determined. The results indicate that the compression effect exerted by the garments significantly influences the clothing physiology comfort of the athlete; a higher compression load leads to more intense sweating and higher skin temperature.
Ključne besede: clothing physiology, tight-fitting sportswear, running test on a treadmill, thermal comfort, skin temperature, perspiration
Objavljeno v DKUM: 21.03.2025; Ogledov: 0; Prenosov: 2
Celotno besedilo (3,48 MB)
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Opis: Background: The crucial steps in beta cell stimulus-secretion coupling upon stimulation with glucose are oscillatory changes in metabolism, membrane potential, intracellular calcium concentration, and exocytosis. The changes in membrane potential consist of bursts of spikes, with silent phases between them being dominated by membrane repolarization and absence of spikes. Assessing intra- and intercellular coupling at the multicellular level is possible with ever-increasing detail, but our current ability to simultaneously resolve spikes from many beta cells remains limited to double-impalement electrophysiological recordings. Methods: Since multicellular calcium imaging of spikes would enable a better understanding of coupling between changes in membrane potential and calcium concentration in beta cell collectives, we set out to design an appropriate methodological approach. Results: Combining the acute tissue slice method with ultrafast calcium imaging, we were able to resolve and quantify individual spikes within bursts at a temporal resolution of >150 Hz over prolonged periods, as well as describe their glucose-dependent properties. In addition, by simultaneous patch-clamp recordings we were able to show that calcium spikes closely follow membrane potential changes. Both bursts and spikes coordinate across islets in the form of intercellular waves, with bursts typically displaying global and spikes more local patterns. Conclusions: This method and the associated findings provide additional insight into the complex signaling within beta cell networks. Once extended to tissue from diabetic animals and human donors, this approach could help us better understand the mechanistic basis of diabetes and find new molecular targets.
Ključne besede: beta cell, calcium imaging, calcium oscillations, calcium spikes, physiology
Objavljeno v DKUM: 24.01.2025; Ogledov: 0; Prenosov: 7
Celotno besedilo (9,70 MB)
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Opis: Bracing has proven to be an effective method for the conventional treatment of scoliosis in young people. A brace, a therapeutic device, covers the upper body and promotes healing by applying pressure to specific areas. However, wearing a scoliosis brace negatively affects the user’s thermo-physiological well-being and often leads to discomfort. In this study, we investigated the influence of T-shirts as an undergarment on the thermo-physiological well-being of the brace wearer. For this purpose, we performed a comparative analysis of six T-shirts made from different special knitted fabrics. We carried out wearing tests in a computer-controlled climate chamber according to a predetermined protocol. The test subject wore the orthopedic brace over the different T-shirts at three different temperatures. The results indicate that the knitted fabrics of undergarments and environmental conditions considerably impact the wearer’s thermo-physiological comfort. In the tests, the T-shirts made from the selected functional fabrics performed very well. The T-shirt made from the classic cotton fabric containing elastane yarn also performed well and was the most environmentally friendly. Currently, due to its lower price and easier availability, this cotton T-shirt can be recommended for wearing under a scoliosis brace.
Ključne besede: clothing physiology, undergarment, knitted fabrics, scoliosis brace, climate chamber, textile material testing
Objavljeno v DKUM: 05.09.2023; Ogledov: 350; Prenosov: 37
Celotno besedilo (3,02 MB)
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