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Matematika A : za študente FKKT UM
Petra Žigert Pleteršek, Matevž Črepnjak, 2022, učbenik za višje in visoke šole

Opis: Visokošolski učbenik predstavlja uvod v matematično analizo na naravoslovno-tehniških fakultetah. Poleg osnovnih pojmov o množicah, logiki in številih so obravnavane realne funkcije in z njimi povezana pojma limite funkcije in zveznosti, ter zaporedja in vrste. Zajete se vsebine diferencialnega računa z aplikacijo odvoda, ter integralni račun.
Ključne besede: logika, množice, realne funkcije, limita in zveznost funkcije, zaporedja, vrste, odvod funkcije, integral
Objavljeno v DKUM: 18.02.2022; Ogledov: 207; Prenosov: 23
.pdf Celotno besedilo (32,77 MB)
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Hellebours niger : systematics, ecology, pollination and production technology
Andrej Šušek, 2021

Opis: The scientific monograph covers the botanical classification of the genus Helleborus L. and the Christmas rose species (Helleborus niger L.), which has undergone numerous changes throughout its botanical history. The Christmas rose is becoming increasingly important in the ornamental plant market. Its characteristic flowering in the coldest months of the year represents a great advantage over many other species of ornamental plants. As the Christmas rose does not require high temperatures to start flowering, its cultivation can be considered affordable and environmentally friendly. The supply of attractive varieties is likely to be one of the key factors that will affect its popularity in the future. The number of genetically improved (bred) varieties is limited on the market, so selective breeding of Christmas rose will become inevitable in the future. The presented results of pollination analyses, related to insect activity, are important for breeding. Observations indicate that the Christmas rose is an entomophilous and a predominantly allogamous species. Knowledge of plant ecology and cultivation technology will also be exceptionally important. In intensive cultivation, the production technology for Christmas roses is still to a large extent incomplete. The monograph includes scientific findings on the ecology and biology of the Christmas rose, its reproductive processes, and the production technology for potted plants. The monograph also presents the results of the study on the effects of beneficial microorganisms (bacteria and endomycorrhizal fungi) on the growth and development of seedlings from in vivo and in vitro environments. The results of the study indicate that biotisation is a useful technology and that inoculation with specific microorganisms has a beneficial effect on growth.
Ključne besede: Christmas rose, Helleborus niger L., systematic, pollination, cultivation, beneficial microorganisms
Objavljeno v DKUM: 28.09.2021; Ogledov: 295; Prenosov: 34
.pdf Celotno besedilo (21,26 MB)
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The impact of the COVID-19 pandemic in 2020 on the quality of STEM higher education
Zorka Novak-Pintarič, Zdravko Kravanja, 2020, kratki znanstveni prispevek

Opis: Pandemic COVID-19 has forced universities around the world to go online virtually overnight. This has been a major challenge, especially for study programmes in STEM areas (Science, Technology, Engineering, Mathematics) where distance learning was not previously preferred. This was mainly due to a large proportion of the experimental laboratory work done by students, which could reach up to half of all contact hours. While the lectures were utilized practically immediately after lockdown using video conferencing systems, the implementation of the practical study contents posed a greater challenge. This paper presents specific adaptations for certain activities in the university education of chemical engineering that had to be implemented quickly, such as laboratory and computer exercises, students' final theses and dissertations, internships, knowledge examination and evaluation. We highlight the most critical activities and most urgent solutions that were initiated. Various measures taken against the spread of the coronavirus had to take into account many uncertainties about the duration of the pandemic to ensure that students acquire the desired competences and skills in time without being physically present in the laboratories. Particular attention is paid to examinations, especially calculus tests, which are difficult to apply remotely. First evaluations show that the adapted learning process has been carried out effectively, but the big unknown is how successfully the students will pass the exams and how the lessons will be conducted in next academic year.
Ključne besede: pandemic, higher education, COVID-19, coronavirus
Objavljeno v DKUM: 16.12.2020; Ogledov: 1490; Prenosov: 125
.pdf Celotno besedilo (682,46 KB)
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Ensemble Docking Coupled to Linear Interaction Energy Calculations for Identification of Coronavirus Main Protease (3CLpro) Non-Covalent Small-Molecule Inhibitors
Marko Jukič, Dušanka Janežič, Urban Bren, 2020, izvirni znanstveni članek

Opis: SARS-CoV-2, or severe acute respiratory syndrome coronavirus 2, represents a new strain of Coronaviridae. In the closing 2019 to early 2020 months, the virus caused a global pandemic of COVID-19 disease. We performed a virtual screening study in order to identify potential inhibitors of the SARS-CoV-2 main viral protease (3CLpro or Mpro). For this purpose, we developed a novel approach using ensemble docking high-throughput virtual screening directly coupled with subsequent Linear Interaction Energy (LIE) calculations to maximize the conformational space sampling and to assess the binding affinity of identified inhibitors. A large database of small commercial compounds was prepared, and top-scoring hits were identified with two compounds singled out, namely 1-[(R)-2-(1,3-benzimidazol-2-yl)-1-pyrrolidinyl]-2-(4-methyl-1,4-diazepan-1-yl)-1-ethanone and [({(S)-1-[(1H-indol-2-yl)methyl]-3-pyrrolidinyl}methyl)amino](5-methyl-2H-pyrazol-3-yl)formaldehyde. Moreover, we obtained a favorable binding free energy of the identified compounds, and using contact analysis we confirmed their stable binding modes in the 3CLpro active site. These compounds will facilitate further 3CLpro inhibitor design.
Ključne besede: COVID-19, SARS-CoV-2, Mpro, 3CLpro, 3C-like protease, virtual screening, inhibitors, in silico drug design, free-energy calculations
Objavljeno v DKUM: 10.12.2020; Ogledov: 571; Prenosov: 78
.pdf Celotno besedilo (2,99 MB)

Separation processes : results of lab work
Maša Knez Marevci, 2020, drugo učno gradivo

Objavljeno v DKUM: 10.08.2020; Ogledov: 420; Prenosov: 21
.pdf Celotno besedilo (532,87 KB)

Upstream / downstream processes : results of lab work
Maša Knez Marevci, Darija Cör, 2020, drugo učno gradivo

Objavljeno v DKUM: 10.08.2020; Ogledov: 505; Prenosov: 18
.pdf Celotno besedilo (426,77 KB)

Pripravljalni in zaključni procesi : navodila za vaje in dnevnik rezultatov laboratorijskih vaj
Maša Knez Marevci, Darija Cör, 2020, drugo učno gradivo

Ključne besede: superkritični fluidi, kalorimetrija, vaje
Objavljeno v DKUM: 10.08.2020; Ogledov: 511; Prenosov: 48
.pdf Celotno besedilo (678,86 KB)

Varnost kemijskih procesov : vaje z navodili
Zorka Novak-Pintarič, Lidija Čuček, 2020, drugo učno gradivo

Ključne besede: kemijski procesi, varnost, vaje
Objavljeno v DKUM: 07.07.2020; Ogledov: 526; Prenosov: 104
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