2.
Usefulness of follicular fluid estradiol and progesterone concentration measurement in predicting outcome of IVF/ICSI natural cyclesVida Gavrić-Lovrec,
Veljko Vlaisavljević,
Borut Kovačič,
Maksimiljan Gorenjak,
Milan Reljič, 2012, izvirni znanstveni članek
Opis: Purpose: The aim of the study was to establish whether follicular fluid (FF) estradiol (E2) and progesterone (P) measurement could be used to predict the outcome of unstimulated IVF/ICSI cycles. Methods: 91 women underwent 150 unstimulated IVF/ICSI cycles (78 IVF and 72 ICSI). Follicular fluid samples were collected at the time of oocyte recovery. Using the ttest, FF E2 and FF P levels and their ratios (FF P/FF E2) were compared between cycles with successful (with oocyte) and unsuccessful (without oocyte) oocyte recovery, between cycles with and without fertilization and between nonconception and conception cycles. Results: The oocyte recovery rate was 86.7% (123/150), the fertilization rate 68.3% (84/123) and the pregnancy rate per oocyte recovery 14.0% (21/150). The average FF E2 level was 3530 +/- 1339 nmol/L, average FF P 20649 +/- 9489 nmol/Land average FF P/FF E2 ratio 7.18 +/- 6.42. There were no statistically significant differences in FF E2, FF P levels and their ratio between cycles with unsuccessful and successful oocyte recovery, between cycles without and with fertilization, and between nonconception and conception cycles. Conclusion: From the FF E2 and P levels and their ratio, it is not possible to make inferences to the likelihood of oocyte recovery, fertilization and conception in unstimulated IVF/ICSI cycles.
Ključne besede: folikularna tekočina, naravni ciklus, estradiol, progesteron, IVF/ICSI izhod
Objavljeno v DKUM: 10.07.2015; Ogledov: 1476; Prenosov: 77
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