1. Mechanisms of post-pancreatitis diabetes mellitus and cystic fibrosis-related diabetes: a review of preclinical studiesEleonóra Gál, Jurij Dolenšek, Andraž Stožer, László Czakó, Attila Ébert, Viktória Venglovecz, 2021, pregledni znanstveni članek Opis: Anatomical proximity and functional correlations between the exocrine and endocrine pancreas warrant reciprocal effects between the two parts. Inflammatory diseases of the exocrine pancreas, such as acute or chronic pancreatitis, or the presence of cystic fibrosis disrupt endocrine function, resulting in diabetes of the exocrine pancreas. Although novel mechanisms are being increasingly identified, the intra- and intercellular pathways regulating exocrine-endocrine interactions are still not fully understood, making the development of new and more effective therapies difficult. Therefore, this review sought to accumulate current knowledge regarding the pathogenesis of diabetes in acute and chronic pancreatitis, as well as cystic fibrosis. Ključne besede: diabetes of the exocrine pancreas, acute pancreatitis, chronic pancreatitis, cystic fibrosis, interaction Objavljeno v DKUM: 14.08.2024; Ogledov: 65; Prenosov: 5 Celotno besedilo (955,04 KB) Gradivo ima več datotek! Več... |
2. Analysis and evaluation of user experience in mobile applications with modern interaction methods : magistrsko deloKatja Frančič, 2024, magistrsko delo Opis: Mobile devices, seamlessly weaving artificial intelligence into their applications, have become indispensable for millions of people in their daily lives. In our master’s thesis, we explored methods for evaluating user experience, focusing on those suitable for modern mobile applications. In the applied phase, participants evaluated three mobile apps using distinct questionnaires. This affirmed the positive correlation between user interface simplicity and enhanced UX, alongside modern interaction methods fostering increased user loyalty. Our findings confirm that post-task questionnaires offer deeper insights into UX, with users showing a preference for completing them. While gender may influence user experience, it's not the sole determinant. Ključne besede: user experience, mobile application, modern interaction methods Objavljeno v DKUM: 01.07.2024; Ogledov: 159; Prenosov: 50 Celotno besedilo (5,40 MB) |
3. Mechanistic insights of polyphenolic compounds from rosemary bound to their protein targets obtained by molecular dynamics simulations and free-energy calculationsSamo Lešnik, Marko Jukič, Urban Bren, 2023, izvirni znanstveni članek Ključne besede: rosemary, carnosic acid, carnosol, rosmanol, rosmarinic acid, polyphenols, molecular docking, molecular dynamics simulations, linear interaction energy calculations, water-mediated hydrogen-bonds, HIV-1 protease, K-RAS protein, factor X Objavljeno v DKUM: 22.04.2024; Ogledov: 185; Prenosov: 15 Celotno besedilo (2,99 MB) Gradivo ima več datotek! Več... |
4. Learning Chinese as a foreign language : an introductionJuliane House, Dániel Z. Kádár, 2023, drugi znanstveni članki Opis: In this introductory paper, we first present the background of the present special issue dedicated to Willis Edmondson. We first point out why Edmondson provided a ground-breaking contribution to the field of applied linguistics and why it is particularly timely to edit a special issue centering on his framework. We also argue that Edmondson's bottom-up and strictly language-anchored view on speech acts and interaction is particularly useful to examine the learning of Chinese as a foreign language, by going beyond exoticizing and overgeneralizing views of the Chinese linguaculture. Second, we briefly present what can be regarded as the heart and soul of the Edmondsonian framework, that is, a typology of speech acts and a related procedure through which the relationship between speech acts in interaction can be captured. Third, we present a research procedure that we outlined in our previous work, and which helps implementing the Edmondsonian model in the pragmatic study of foreign language learning. Finally, we present the contents of the special issue. Ključne besede: Chinese, interaction, speech acts, second language pragmatics Objavljeno v DKUM: 21.02.2024; Ogledov: 341; Prenosov: 21 Celotno besedilo (348,04 KB) Gradivo ima več datotek! Več... |
5. Learning Chinese in a study abroad context : the case of ritual congratulatingJuliane House, Dániel Z. Kádár, 2023, izvirni znanstveni članek Opis: In this paper, we explore how and why the realisation of the ritual act of congratulating may turn out to be challenging for foreign learners of Chinese. Congratulating and other ceremonial ritual acts are not only used when someone participates in an actual ritual event: they are also required when they are mentioned in mundane events, like casual interactions when someone talks about a family birthday or wedding. We define congratulation as an interactional move and systematically examine its conventional realisation patterns through a typology of speech acts. We approach congratulating moves by combining a speech act-anchored analysis with the field of study abroad and interaction ritual research. The results of our analysis show that various ritual occasions may trigger different types of inappropriate uses of congratulating by foreign learners of Chinese. Ključne besede: Chinese, interaction rituals, speech acts, study abroad, congratulating Objavljeno v DKUM: 20.02.2024; Ogledov: 445; Prenosov: 20 Celotno besedilo (462,61 KB) Gradivo ima več datotek! Več... |
6. Evaluation of dynamic soil pressures acting on rigid culverts : shaking-table testsDeniz Ulgen, Mehmet Yener Özkan, 2016, izvirni znanstveni članek Opis: The seismic safety of underground structures (culvert, subway, natural-gas and water-sewage systems) plays a major role in sustainable public safety and urban development. Very few experimental data are currently available and there is no generally accepted procedure to estimate the dynamic pressures acting on these underground structures. This study aims to enhance the state of the prevalent information necessary to understand the dynamic behaviour of box culverts and the stresses acting under dynamic excitations through experimental analyses. For this purpose, a series of shaking-table tests were conducted on box-type culverts buried in dry sand. To simulate the free-field boundary conditions, a laminar box was designed and manufactured for use with a 1-g shake table. Two culvert models having different rigidities were tested under various harmonic motions in order to examine the effect of the flexibility ratio on dynamic lateral soil pressures. Based on the test results, a simplified dynamic pressure distribution acting on the sidewalls of the culvert model was suggested. Then, a dynamic lateral coefficient was defined for the proposed peak pressure value in the distribution. The values of this coefficient were obtained as a function of the shear strain by considering the relative stiffness between the soil and the underground structure. Ključne besede: box culvert, dynamic earth pressure, shaking table, dynamic soil-structure interaction, laminar box, dynamic lateral coefficient Objavljeno v DKUM: 18.06.2018; Ogledov: 1000; Prenosov: 223 Celotno besedilo (584,65 KB) Gradivo ima več datotek! Več... |
7. A comparison of linear and nonlinear seismic tunnel-ground interaction analysesElefterija Zlatanović, Marina Trajković-Milenković, Dragan Lukić, Stanko Brčić, Vlatko Šešov, 2016, izvirni znanstveni članek Opis: In order to study the effects of a seismically induced tunnel–ground interaction, two-dimensional numerical analyses are performed using the sofware ANSYS. The study employs a coupled beam–spring model subjected to earthquake loading that is simulated under pure shear conditions and determined by a free-field ground-response analysis using the code EERA. The properties of the soil material are considered as both linear and nonlinear. The results obtained by linear dynamic analyses are compared with state-of-practice analytical elastic solutions. A comparison of the results of both linear and nonlinear analyses is also performed, and significant differences, as well as important factors influencing the tunnel–ground interaction for both cases, are evaluated. Ključne besede: circular tunnel, linear/nonlinear soil behaviour, beam–spring model, plane-strain conditions, simplified dynamic FE analysis, soil–structure interaction Objavljeno v DKUM: 18.06.2018; Ogledov: 1339; Prenosov: 80 Celotno besedilo (1,57 MB) Gradivo ima več datotek! Več... |
8. The limit values and the distribution of three-dimensional passive earth pressuresStanislav Škrabl, 2008, izvirni znanstveni članek Opis: This paper presents a novel approach to the determination of the critical distribution and limit values of three-dimensional passive soil pressures acting on flexible walls following the upper-bound method within the framework of the limit-analysis theory. The method of limit analysis with a set of three-dimensional kinematically admissible hyperbolic translational failure mechanisms is used to determine the critical distribution of the passive pressures along the retaining structurećs height. The intensity of thepassive pressures is gradually determined with the mentioned translational failure mechanisms in the top-down direction. Thus, the critical distribution,the trust point and the resultant of the passive pressures that can be activated at the limit state for the chosen kinematic model are obtained. The results of the analyses show that the total sum of passive pressures, considering the critical distribution, is lower than the comparable values published in the literature. Furthermore, the trust point of the passive pressure resultant is independent of the friction between the retaining structures and the soil. Ključne besede: limit analysis, earth pressure, passive pressure, failure surface, soil-structure interaction Objavljeno v DKUM: 05.06.2018; Ogledov: 1160; Prenosov: 168 Celotno besedilo (331,84 KB) Gradivo ima več datotek! Več... |
9. Interactional approach of cantilever pile walls analysisStanislav Škrabl, 2006, izvirni znanstveni članek Opis: This paper proposes a new method for the geomechanical analysis and design of cantilever retaining structures. It is based on the limit equilibrium method, but it uses some additional conditions for interaction between the retaining structure and the ground, when referring to the distribution of the mobilized earth pressures on the structure. The greatest benefit of the proposed method is shown in the analysis of structures of layered ground (heterogeneous above the dredge level and homogeneous below it), embedded in frictional and cohesive materials, and in the possibility of considering the influence of surcharge loadings on the active or passive side of the retaining structure. When analyzing such cases in practice, the proposed method gives results which are in better agreement with the results of FEM based elasto-plastic interaction analyses than with the results of currently used methods. At the same time, its results are in accordance with those published for homogeneaus cohesionless ground. Since in practice almost all retaining structures are erected in layered ground (heterogeneaus above the dredge level and homogeneous below it), the proposed method is very convenient and applicable for the analyses and design of cantilever structures under arbitrary geomechanical conditions. Ključne besede: geomechanics, soil-structure interaction, retaining walls, embedment, cantilevers, earth pressure, pressure distribution, friction soil - wall, limit analysis, shear forces Objavljeno v DKUM: 17.05.2018; Ogledov: 1460; Prenosov: 83 Celotno besedilo (411,22 KB) Gradivo ima več datotek! Več... |
10. Green's function for an elastic layer loaded harmonically on its surfaceTomaž Pliberšek, Andrej Štrukelj, Andrej Umek, 2005, izvirni znanstveni članek Opis: The Green's function in surface displacement plays an important role in soil structure interaction. In evaluating the Green's function, several difficulties occur because it is formulated in the infinite integral form. This paper outlines a method of analyzing the steady-state dynamic response of an elastic layer subjected to general point load excitation. It is assumed that the load is applied at the surface. The application Hankel integral transform, to the governing differential equations and boundary conditions yields the response displacements at the surface in integral representation. It will be shown that these semi-infinite integrals can be reduced to the integral with the finite range of integration, which can be efficiently taken numerically. The numerical results are presented, which show the efficiency of the developed procedure. Ključne besede: civil engineering, geomechanics, soil-structure interaction, layered halfspace, Green's function, elastodynamics Objavljeno v DKUM: 15.05.2018; Ogledov: 1665; Prenosov: 102 Celotno besedilo (375,59 KB) Gradivo ima več datotek! Več... |