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1.
The impact of economic growth on the market and communication value of real estate
Igor Pšunder, Mirko Pšunder, Ksenija Golob, 2013, kratki znanstveni prispevek

Opis: In the last five years is on the Slovenian real estate market observed highly trend in market volatility in property prices. Developments in the housing market have drastically changed and also represent an important indicator of overall economic trends. There is a lot of factors that affect the market price of real estate. With research we were focus on the problem of the impactof economic growth in the market value of real estate in Slovenia. We were present trend of economic growth in the last decade and its impact on growth or decline in real estate transactions. We were also established if declining real estate transactions affect the provision of more and bigger discounts on the sale of real estate. Among the research parameters, we were presented as well as their interdependence. With constant monitoring of parameters and statistical methods, we were collect data on the impact of economic growth and offered discounts on the real estate market prices, for future periods. The aim of the research is to define those factors that need to be considered for the analytical prediction of the trend of market prices and selling real estate in the future.The results obtained will help real estate valuers in the drawing up of reports assessing the value of real estate.
Ključne besede: nepremičninski trg, ekonomska rast, cena nepremičnin, statistične metode, real estate market, economic growth, market factors, statistical method
Objavljeno: 10.07.2015; Ogledov: 919; Prenosov: 15
URL Povezava na celotno besedilo

2.
Release of growth factors after mechanical and chemical pleurodesis for treatment of malignant pleural effusion
Aljaž Hojski, Maja Leitgeb, Anton Crnjac, 2015, izvirni znanstveni članek

Opis: Background: Growth factors are key inducers of fibrosis but can also mediate inflammatory responses resulting in increasing pleural effusion and acute respiratory distress syndrome. The primary aim of the study was to analyse growth factors release after performing chemical and mechanical pleurodesis in the first 48 hours at the patients with malignant pleural effusion. The secondary endpoints were to evaluate the effectiveness of the both pleurodeses, symptoms release and the quality of life of patients after the treatment. Patients and methods: A prospective randomized study included 36 consecutive female patients with breast carcinoma and malignant pleural effusion in an intention-to-treat analysis. We treated 18 patients by means of thoracoscopic mechanical pleurodesis and 18 patients by chemical pleurodesis with talcum applied over a chest tube. We gathered the pleural fluid and serum samples in the following 48 hours under a dedicated protocol and tested them for growth factors levels. A quality of life and visual analogue pain score surveys were also performed. Results: Median measured serum vascular endothelial growth factor (VEGF) level after chemical pleurodesis was 930.68 pg/ml (95% CI: 388.22-4656.65) and after mechanical pleurodesis 808.54 pg/ml. (95% CI: 463.20-1235.13) (p = 0.103). Median pleural levels of transforming growth factor (TGF) ß1 were higher after performing mechanical pleurodesis (4814.00 pg/ml [95% CI: 2726.51-7292.94]) when compared to those after performing chemical pleurodesis (1976.50 pg/ml [95% CI: 1659.82-5136.26]) (p = 0.078). We observed similar results for fibroblast growth factor (FGF) ß; the serum level was higher after mechanical pleurodesis (30.45 pg/ml [95% CI: 20.40-59.42]), compared to those after chemical pleurodesis (13.39 pg/ml [95% CI: 5.04-74.60]) (p = 0.076). Mechanical pleurodesis was equally effective as chemical pleurodesis in terms of hospital stay, pleural effusion re-accumulation, requiring of additional thoracentesis, median overall survival, but, it shortened the mean thoracic drainage duration (p = 0.030) and resulted in a higher symptoms release and in a better quality of life (p = 0.047). Conclusions: We recorded an increase in serum VEGF levels after chemical pleurodesis, however on the contrary, an increase in the pleural fluid level of TGF%1 and FGF%] after mechanical pleurodesis with respect to compared group. Although the differences did not reach statistical significance, VEGF, TGFß1 and FGFß remain the most interesting parameters for future research. Considering the mechanisms of growth factors action, we conclude that in our study group mechanical pleurodesis might be more efficient in terms of growth factors release, thoracic drainage duration and resulted in a higher symptoms release and in a better quality of life than chemical pleurodesis.
Ključne besede: malignant pleural effusion, pleurodesis, growth factors, quality of life
Objavljeno: 05.04.2017; Ogledov: 535; Prenosov: 42
.pdf Celotno besedilo (689,93 KB)
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