1. A monocarbonyl curcuminoid derivative inhibits the activity of human glutathione transferase A4-4 and chemosensitizes glioblastoma cells to temozolomideSteliana Tsouri, Evanthia Tselo, Georgios E. Premetis, Veronika Furlan, Panagiota D. Pantiora, Barbara Mavroidi, Dimitris Matiadis, Maria Pelecanou, Anastassios C. Papageorgiou, Urban Bren, Marina Sagnou, Nikolaos E. Labrou, 2024, izvirni znanstveni članek Ključne besede: chemosensitization, chemoresistance, curcumin, glioblastoma, human glutathione transferase A4-4, ellagic acid, monocarbonyl curcumin derivatives, GST inhibition, temozolomide sensitization
Objavljeno v DKUM: 23.08.2024; Ogledov: 66; Prenosov: 2
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2. Optimal positioning of mobile cranes on construction sites using nonlinear programming with discontinuous derivativesMatjaž Hozjan, Uroš Klanšek, 2023, izvirni znanstveni članek Opis: Mobile cranes represent conventional construction machinery that is indispensable for the erection of most prefabricated buildings, especially those containing heavy components. However, it is also common knowledge that the engagement of these machines has a significant influence on the environment, various social aspects of the construction process, and its economic benefits. Optimal positioning of the mobile crane on the construction site, primarily driven by the contractor’s interest to perform assembly operations with expensive machinery as effectively as possible, considerably reduces not only the costs of engaging such a machine but indirectly also its negative impacts on construction sustainability. This paper discusses an exact nonlinear model for the optimization task. The optimization model consists of a cost objective function that is subject to various duration and positioning constraints for the mobile crane, including bounds on its degrees of freedom of movement and stop positions. Because the model formulation includes discontinuous and non-smooth expressions, nonlinear programming with discontinuous derivatives (DNLP) was employed to ensure the optimal solution was reached. The model provides the mobile crane operator with exact key information that enables the complete and optimal assembly of the building structure under consideration. Additionally, the information gained on the optimal distribution of the mobile crane rental period to assembly operations allows for a detailed duration analysis of the entire process of building structure erection, which can be used for its further improvement. An application example is given in this study to demonstrate the advantages of the proposed approach.
Ključne besede: construction sustainability, mobile crane, nonlinear programming with discontinuous derivatives, optimization, positioning
Objavljeno v DKUM: 18.12.2023; Ogledov: 403; Prenosov: 14
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3. Reduction of the mean hedging transaction costsMiklavž Mastinšek, 2015, izvirni znanstveni članek Opis: Transaction costs of derivative hedging appear in financial markets. This paper considers the problem of delta hedging and the reduction of expected proportional transaction costs. In the literature the expected approximate proportional transaction costs are customarily estimated by the gamma term, usually the largest term of the associated series expansion. However, when options are to expire in a month or few weeks, other terms may become even larger so that more precise estimates are needed. In this paper, different higher-order estimates of proportional transaction costs are analyzed. The problem of the reduction of expected transaction costs is considered. As a result, a suitably adjusted delta is given, for which the expected approximate proportional transaction costs can be reduced. The order of the mean and the variance of the hedging error can be preserved. Several examples are provided.
Ključne besede: derivatives, delta hedging, transaction costs, hedging error
Objavljeno v DKUM: 03.04.2017; Ogledov: 1276; Prenosov: 178
Celotno besedilo (662,21 KB)
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4. l-(6-0-Acetil-3, 4-Dideoksi-3-Fluoro-ß-D-Glicero-Hex-3-enopiranozil-2-Uloza)-N4-Benzoil Citozin je močan inhibitor replikacije pseudorabies virusa v okuženih celicahTanja Botić, Stella Manta, Dimitri Komiotis, Francois Lefevre, Avrelija Cencič, 2009, izvirni znanstveni članek Ključne besede: fluoro-glukopiranozil derivati, ketonukleozidi, antivirusna aktivnost, DNA virus, fluoro-glucopyranosyl derivatives, ketonucleosides, antiviral activity, DNA virus
Objavljeno v DKUM: 10.07.2015; Ogledov: 1160; Prenosov: 38
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5. Technical analysis of the financial markets : a comprehensive guide to trading methods and applicationsJohn J. Murphy, priročnik Ključne besede: financial market, finances, financial systems, securities, stock market, indicators, derivatives, futures, options, interests, cycles, trading, financial management, methods, application, technical analysis, financial analysis, exchange, trends, guidebooks
Objavljeno v DKUM: 01.06.2012; Ogledov: 3455; Prenosov: 241
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