Iskanje po katalogu digitalne knjižnice

Opis: Background and purpose: The aim of this study was to examine the risk factors, prodromal symptoms, non-motor symptoms (NMS), and motor symptoms (MS) in different Parkinson’s disease (PD) non-motor subtypes, classified using newly established criteria and a data-driven approach. Methods: A total of 168 patients with idiopathic PD underwent comprehensive NMS and MS examinations. NMS were assessed by the Non-Motor Symptom Scale (NMSS), Montreal Cognitive Assessment (MoCA), Hamilton Depression Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), REM Sleep Behavior Disorder Screening Questionnaire (RBDSQ), Epworth Sleepiness Scale (ESS), Starkstein Apathy Scale (SAS) and Fatigue Severity Scale (FSS). Motor subtypes were classified based on Stebbins’ method. Patients were classified into groups of three NMS subtypes (cortical, limbic, and brainstem) based on the newly designed inclusion criteria. Further, data-driven clustering was performed as an alternative, statistical learning-based classification approach. The two classification approaches were compared for consistency. Results: We identified 38 (22.6%) patients with the cortical subtype, 48 (28.6%) with the limbic, and 82 (48.8%) patients with the brainstem NMS PD subtype. Using a data-driven approach, we identified five different clusters. Three corresponded to the cortical, limbic, and brainstem subtypes, while the two additional clusters may have represented patients with early and advanced PD. Pearson chi-square test of independence revealed that a priori classification and cluster membership were significantly related to one another with a large effect size (χ2(8) = 175.001, p < 0.001, Cramer’s V = 0.722). The demographic and clinical profiles differed between NMS subtypes and clusters. Conclusion: Using the actuarial and clustering approach, marked differences between individual NMS subtypes were found. The newly established criteria have potential as a simplified tool for future clinical research of NMS subtypes of Parkinson’s disease.
Ključne besede: Parkinson’s disease, non-motor symptoms subtypes, a priori classification, cluster analysis
Objavljeno v DKUM: 07.04.2025; Ogledov: 0; Prenosov: 3
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Opis: The goal of this research was to investigate the level of digital divide among selected European countries according to the big data usage among their enterprises. For that purpose, we apply the K-means clustering methodology on the Eurostat data about the big data usage in European enterprises. The results indicate that there is a significant difference between selected European countries according to the overall usage of big data in their enterprises. Moreover, the enterprises that use internal experts also used diverse big data sources. Since the usage of diverse big data sources allows enterprises to gather more relevant information about their customers and competitors, this indicates that enterprises with stronger internal big data expertise also have a better chance of building strong competitiveness based on big data utilization. Finally, the substantial differences among the industries were found according to the level of big data usage.
Ključne besede: big data, cluster analysis, digital divide, k-means, enterprise, industry, Europe, quality
Objavljeno v DKUM: 14.01.2025; Ogledov: 0; Prenosov: 3
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Opis: Fifty samples of natural mineral waters from springs in Slovenia, Hungary, Germany, Czech Republic and further countries of former Yugoslavia have been analysed. The mass concentration of cations ($Na^+$, $K^+$, $Ca^{2+}$, $Mg^{2+}$, $Fe^{2+}$, $Mn^{2+}$, $NH^+_4$) and anions ($F^-$, $Cl^-$, $I^-$, $NO^-_3$, $SO_4^{2-}$, $HCO_3^-$), the spring temperature, pH, conductivity and carbon dioxide mass concentration have been measured using standard analytical methods. Appropriate statistical methods and different chemometric tools were used to evaluate the obtained data, namely, (i) descriptive statistics, (ii) principal component analysis (PCA), (iii) cluster analysis, and (iv) linear discriminant analysis (LDA). It was confirmed that Slovenian natural mineral water samples differ most from the German ones but are relatively similar to the Czech and Hungarian ones. Water samples from Hungary are similar to waters from the eastern part of Slovenia.
Ključne besede: natural mineral water, ion determination, principal component analysis, cluster analysis, linear discriminant analysis
Objavljeno v DKUM: 21.12.2015; Ogledov: 1866; Prenosov: 103
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Ključne besede: information society, informatics, information technology, computer networks, internet, enterprise, electronic commerce, electronic marketing, marketing strategy, new economy, data warehousing, data base, data analysis, security, application, data structures, customer, information resources, consumer, statistics, cluster analysis, neural networks, data, trends, cases, case study
Objavljeno v DKUM: 01.06.2012; Ogledov: 2743; Prenosov: 87
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