1. AOP-based transformation of abacavir in different environments: evolution profile of descyclopropyl-abacavir and in silico toxicity assessment of the main transformation productsEleni Evgenidou, Konstantina Vasilopoulou, Lelouda-Athanasia Koronaiou, George Z. Kyzas, Dimitrios Bikiaris, Dimitra A. Lambropoulou, 2023, izvirni znanstveni članek Ključne besede: abacavir, antiviral drug, AOPs, transformation products, ECOSAR, evolution profiles Objavljeno v DKUM: 05.04.2024; Ogledov: 276; Prenosov: 7 Celotno besedilo (2,56 MB) Gradivo ima več datotek! Več... |
2. Private forest owner willingness to mobilise wood from dense, small-diameter tree standsMatevž Triplat, Satu Helenius, Ruben Laina, Nike Krajnc, Thomas Kronholm, Zdenka Ženko, Teppo Hujala, 2023, izvirni znanstveni članek Opis: Forests are a source of renewable biomass, and their utilisation will play a vital role in the transition towards a climate-neutral economy. Small-diameter tree management could contribute to this transition via providing renewable biomass for sustainable uses and fostering tree growth towards long-lifecycle bioproducts. The utilisation of small-diameter trees in the EU is still low since new technologies and work models are required to make the operations economically profitable, environmentally sound, and socially attractive. The supply of biomass from small-diameter tree stands is dependent on forest owners with diverse perceptions on their forests and diverse ownership objectives. However, there is scarce research on forest owner perceptions on small-diameter tree management, which encompasses home consumption, self-active work, and commercial forestry services. A survey in four EU countries was designed to identify the main factors affecting the motivation of forest owners to mobilise biomass from small-diameter stands. Factor and clustering analyses were used to identify four forest owner segments: weakly-engaged traders, well-being seekers, self-active profit-seekers, and well-informed service users. The willingness to utilise biomass from small-diameter tree stands and participate in the market was shaped by forest owner knowledge of forestry, economic and socio-cultural motivations, and sensitivity to service offerings. Forest owner preferences for market participation are heterogenous, and thus different policy implementation approaches are needed and proposed. Ključne besede: profili strank, faktorska analiza, gozdarske storitve, upravljavski cilji, biomasa, komunikacijske strategije, customer profiles, factor analysis, forestry services, management objectives, biomass, communication strategies Objavljeno v DKUM: 10.07.2023; Ogledov: 475; Prenosov: 35 Celotno besedilo (1,51 MB) Gradivo ima več datotek! Več... |
3. PET film production : a report for AMPEF - EUROPE (Association of Manufacturers of Polyester Films), Brussels, January 1998Ian Boustead, 1998, tehnično poročilo Ključne besede: polymers, polyethylene terephthalate, structural analysis, structure, ethylene, PET, commercial policy, production, system examined, ecology, presentation, profiles, results, tables, methodology, energy Objavljeno v DKUM: 01.06.2012; Ogledov: 2002; Prenosov: 54 Povezava na celotno besedilo |
4. Multivariate data analysis of erythrocyte membrane phospholipid fatty acid profiles in the discrimination between normal blood tissue and various disease statesZdenka Cencič-Kodba, Darinka Brodnjak-Vončina, Marjana Novič, Uroš Potočnik, 2010, izvirni znanstveni članek Opis: The investigation presented here aims to compare the fatty acid composition of red blood cells of patients with different disease states and to test the hypothesis that the changes in fatty acid profiles derived from erythrocyte phospholipids might be relevant to various diseases. The study sample consisted of 342 blood donors, among them 135 with inflammatory bowel disease, 53 with uterine leiomyoma, 14 with verified absence of uterine leiomyoma, 52 with asthma, 18 with colon adenomas, and 70 blood samples without any of mentioned diseases that was used as a control group. After the isolation of erythrocytes from blood samples, total extracted lipids were separated by solid-phase extraction (SPE) into non polar lipids and polar phospholipids. After the saponification of phospholipid fraction, the esterification process followed with boron trifluoride-methanol reagent. The fatty acid methyl ester (FAME) composition of the total red blood cell phospholipid fraction was analyzed by gas chromatography (GC) with flame ionization detector (FID). Additionally two fatty aldehyde dimethyl acetals (hexadecanal and octadecanal dimethyl acetals; 16:0 DMA and 18:0 DMA) derived from erythrocyte membrane plasmalogen phospholipids were also determined. The resulting fatty acid and plasmalogen linked fatty acid composition was evaluated by the principal component analysis (PCA). We demonstrated decreased levels of omega-3 polyunsaturated fatty acids (n-3 PUFAs) in red blood cell membrane of patients with colon adenomas. Also, a large negative correlation was observed among all samples between the quantity of saturated acids and arachidonic (20:4n6) acid as well as saturated acids and adrenic (22:4n6) acid. In PCA score plot a group of female donors is distinguished mainly by the content of linoleic (18:2n6) acid; a small subgroup shows its concentration highly above the average value. At the same time, the same subgroup has both dimethyl acetals below the average concentrations. The study demonstrates feasibility of multivariate data analysis in discrimination of patients with different diseases according to fatty acid profile and suggests considerable differences in membrane fatty acid profiles in patients with various disease states. Ključne besede: erythrocyte phospholipids, cell membrane, fatty acid profiles, differentiation, disease state, gas chromatography, principal component analysis Objavljeno v DKUM: 31.05.2012; Ogledov: 3112; Prenosov: 95 Celotno besedilo (280,87 KB) Gradivo ima več datotek! Več... |
5. A safety shell for UML-RT projectsRoman Gumzej, Wolfgang A. Halang, 2008, objavljeni znanstveni prispevek na konferenci Opis: A safety shell pattern was defined based on a reconfiguration management pattern, and inspired by the architectural specifications in Specification PEARL. It is meant to be used for real-time applications to be developed with UML-RT as described. The implementation of the safety shell features as defined by in [8], namely its timing and state guards as well as I/O protection and exception handling mechanisms, is explained. The pattern is parameterised by defining the properties of its components as well as by defining the mapping between software and hardware architectures. Initial and alternative execution scenarios as well as the method for switching between them are defined. The goal pursued with the safety shell is to obtain clearly specified operation scenarios with well defined transitions between them. To achieve safe and timely operation, the pattern must provide safety shell mechanisms for an application designed, i.e., enable its predictable deterministic and temporally predictable operation now and in the future. Ključne besede: real-time systems, embedded systems, UML profiles, UML patterns, safety Objavljeno v DKUM: 31.05.2012; Ogledov: 1770; Prenosov: 171 Povezava na celotno besedilo |
6. A novel approach for assuring and following inoculum activity during kefir grains growth studies : application of dynamic pH profilesMarko Tramšek, Andreja Goršek, 2007, izvirni znanstveni članek Opis: The profiles of kefir grains growth curves strongly depend on bioprocess conditions and inoculum viability. Therefore, accurate growth curve studies require the use of optimally active kefir grains as inoculum. Accordingly, the main objective of our study was experimental optimization of classic kefir grains activation procedure and afterwards, comparison among growth curves of differently activated kefir grains. For this purpose some experiments were initially performed in computer-controlled RC1 reactor provided data of dynamic pH profiles during batch propagation of differently activated grains. Experimental data were mathematically analyzed and using the special methodology of minimizing the absolute deviation of pH(t) profiles the minimal time for grains activation was determined. We established that optimal inoculum activity could be ensured only by the kefir grains, which were previously activated at least over eleven successive days. In the second part of research the growth curve of optimally activated kefir grains was constructed using experimental measurements and fitted with Gompertz model. The present results were compared with the results obtained by our previous study, where classically activated grains were used. We established that, inspite of equal daily kefir grain mass increase, considerable difference in growth curves of differently activated kefir grains exist. Ključne besede: chemical processing, kefir grains, growth curve, minimal activation time, dynamic pH profiles, Gompertz model Objavljeno v DKUM: 31.05.2012; Ogledov: 2134; Prenosov: 119 Celotno besedilo (384,93 KB) Gradivo ima več datotek! Več... |
7. A reconfiguration pattern for distributed embedded systemsRoman Gumzej, Matjaž Colnarič, Wolfgang A. Halang, 2007, izvirni znanstveni članek Opis: A reconfiguration pattern for UML-based projects of embedded (real-time) systems is defined. It enables to set up hardware/software configurations, and to specify conditions and methods for dynamic reconfiguration. The reconfiguration pattern was inspired by the reconfiguration management solution of the Specification PEARL methodology, which is based on the standard for Multiprocessor PEARL whose original idea it was to extend the language to enable the programming of distributed real-time applications in PEARL. In Specification PEARL, the possibility for abstract descriptions of hardware and software architectures and for defining mappings from software to hardware components has been enhanced in correspondence with the standard. Here, a UML pattern for reconfiguration management in distributed embedded applications based on concepts from Specification PEARL is presented. Its behavioural, structural and functional aspects are outlined. It addresses stereotype entities from the Specification PEARL language, which were joined in a UML profile, and outlines the related reconfiguration management mechanisms, which were carried over to the mentioned UML pattern. The proposed reconfiguration pattern is to facilitate the development of distributed embedded application in UML with consistent and temporally predictable reconfiguration support. It should also support and enhance the applicationsć flexibility and portability. Ključne besede: real-time, distributed, embedded systems, dynamic reconfiguration, UML profiles and patterns, UML-RT, specification PEARL Objavljeno v DKUM: 31.05.2012; Ogledov: 2018; Prenosov: 108 Povezava na celotno besedilo |
8. QoS-oriented design of embedded systems with specification PEARLRoman Gumzej, Wolfgang A. Halang, 2007, izvirni znanstveni članek Opis: Only recently have methodical tools adequate to design real-time systems been formally introduced in design methodologies. Naturally, they were present fromthe beginning, but due to the large diversity of embedded systemsć areas of deployment, specially dedicated formalisms have been developed and used. High-level language programming and integration of modeling formalisms into design methods eased the development of more complex real-time applications. With the emerging object-oriented programming languages and design methods, their integration into larger information systems has become more transparent. It was the UML methodology, however, which eventually merged also the design methods and concepts of real-time systems into a consistent whole. It took a large consortium and a long process to persuade industry of the benefits the new integral methodology can offer. On the other hand, there are some trade-offs, and there are some features not completely covered, yet. Here, a different, more straightforward approach to program and design (embedded) real-time systems is presented. Since it emerged from the real-time community, it includes most features relevant there. Independent of the UML profile for schedulability, performance and time specification, a profile was devised for use in PEARL-oriented UML design. The strengths of the mentioned language and design methods for QoS-oriented design of (embedded) real-time systems are emphasised throughout this article. Ključne besede: real time systems, embedded systems, quality of service, co-design, co-simulation, safety, dependability, security, timeliness, determinism, readiness, reliability, portability, flexibility, specification PEARL, UML profiles, patterns Objavljeno v DKUM: 31.05.2012; Ogledov: 2564; Prenosov: 130 Povezava na celotno besedilo |