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Govor treh Bistric v Prekmurju
Nina Zver, 2023, izvirni znanstveni članek

Opis: Krajevni govor treh Bistric – Gornje, Srednje in Dolnje – uvrščamo v južno ali dólinsko različico prekmurskega narečja panonske narečne skupine, vendar je ta v nekaterih pogledih bolj podoben govorom prleškega in medžimurskega narečja kot sosednjim govorom na Dólinskem. Gradivsko podprt prispevek obravnava tiste glasoslovne, oblikoslovne in besedne pojave v krajevnem govoru treh Bistric, ki so razlikovalni v odnosu do bližnjih krajevnih govorov in so jih jezikoslovci prepogosto posploševali za vse prekmursko narečje. Dodan je tudi seznam ledinskih imen na območju Gornje, Srednje in Dolnje Bistrice.
Ključne besede: dialektologija, prekmursko narečje, dolinski govori, glasoslovje, oblikoslovje, besedje, ledinska imena
Objavljeno v DKUM: 17.05.2024; Ogledov: 49; Prenosov: 0
.pdf Celotno besedilo (2,90 MB)
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3.
Klavirska dela Ravela in Debussyja v povezavi z impresionističnim slikarstvom : magistrsko delo
Nina Osenjak, 2024, magistrsko delo

Opis: Impresionizem je umetnostni slog, ki se je najprej razvil v slikarstvu in kasneje v glasbi. Razvil se je v poznem 19. stoletju v prestolnici Francije. Impresionistični slikarji so s svojim nekonvencionalnim pristopom k obravnavanju barv, ustvarjanjem v naravi ter uporabo kratkih, nejasnih potez in linij skupaj z upodabljanjem trenutnih vtisov in naravnih motivov močno vplivali na takratne skladatelje, zlasti na Debussyja ter posredno tudi na Ravela. Pod močnim vplivom simbolizma sta skladatelja zamajala temelje tradicionalne harmonije z vpeljavo novih lestvic in modalnosti, obogatila akorde s kromatičnimi odtenki, svobodno uporabljala disonance, eksotične ritme, zvočne efekte in ter razširila zvočno paleto z vključevanjem manj uveljavljenih instrumentov. V osrednjem delu zaključnega dela obravnavamo in raziskujemo vzporednice med francoskimi impresionističnimi slikarji in klavirskimi deli glasbenih impresionistov, pri čemer v ospredje postavljamo Ravela. Na podlagi literature ugotavljamo njegovo povezavo z njegovimi sodobniki, pri čemer se kaže vpliv predvsem Debussyja in ustvarjalcev kot sta Satie in Fauré. Čeprav so delili nekatere skupne estetske in slogovne značilnosti, je Ravel sčasoma oblikoval svoj prepoznaven glasbeni jezik, ki sega preko zgolj impresionističnih okvirjev. Z večjim poudarkom na klasicističnih oblikovalnih nazorih ga označujemo kot ''klasika impresionizma''. V zaključnem delu na podlagi Skrjabinove sinestezije, kjer povežemo barvo in zvok, in izbranih štirih klavirskih skladbah Ravela in Debussyja iščemo vzporednice z impresionističnimi slikarji.
Ključne besede: impresionizem, slikarstvo, glasba, poezija, klavir, Claude Debussy, Maurice Ravel, sinestezija
Objavljeno v DKUM: 15.05.2024; Ogledov: 80; Prenosov: 6
.pdf Celotno besedilo (6,24 MB)

4.
Merilna negotovost sistema za oceno in napoved atmosferskih pogojev vzdolž daljnovodov
Nina Miklavčič, 2024, magistrsko delo

Opis: Moderen elektroenergetski sistem se vedno bolj osredotoča na dinamično določanje termičnega toka v električnih vodnikih. Pravilna določitev dovoljenega termičnega toka predstavlja osrednji element pri obvladovanju tokovne obremenitve in ohranjanju učinkovitega delovanja elektroenergetskega omrežja. S pomočjo vzpostavitve merilnih postaj smo izračunali kombinirano merilno negotovost termičnega toka napovedanih atmosferskih spremenljivk z mikroskalnim meteorološkim modelom CALMET. Poznavanje merilne negotovosti termičnega toka pri dinamičnem določanju meja je ključnega pomena za obvladovanje zanesljivega prenosa električne energije in preprečevanje preobremenitev v elektroenergetskem omrežju.
Ključne besede: merilna negotovost, mikroskalni meteorološki model, dinamično termično ocenjevanje, meteorološke postaje
Objavljeno v DKUM: 26.04.2024; Ogledov: 151; Prenosov: 25
.pdf Celotno besedilo (7,60 MB)

5.
Strateške možnosti rasti podjetja x: analiza generične in diverzificirane rasti
Nina Skrivarnik, 2024, magistrsko delo

Opis: V magistrskem delu smo preučevali strategije rasti v podjetju X. Obravnavano podjetje se v glavnem ukvarja z elektro inštalacijami in je na trgu prisotno že 28 let. Magistrsko delo je sestavljeno iz dveh delov; teoretičnega in aplikativnega. V teoretičnem delu smo obravnavali faze razvoja podjetja in koncepte ter strategije rasti v podjetju. Povzeli smo definicije različnih avtorjev in jih med seboj primerjali. Opisali smo značilnosti generične in diverzificirane rasti in izpostavili nevarnosti, ki lahko pretijo podjetju ob njegovi rasti. Pojasnili smo še ostale izvedbene rasti v podjetju in našteli možnosti povezovanja z ostalimi podjetji, za boljši konkurenčni položaj. Nato smo se dotaknili še ekonomskih kazalnikov v podjetju, ki so pomembni pri ocenjevanju uspešnosti njegovega poslovanja. V drugem, aplikativnem delu naloge smo zbrana teoretična izhodišča uporabili na primeru podjetja X. Po osnovni predstavitvi podjetja, smo zanj sestavili vizijo in politiko podjetja, ki smo jo lahko določili na podlagi intervjuja s lastnikom. Za podjetje X smo izdelali SWOT matriko, nato pa s pomočjo orodja GVIN opravili konkurenčno analizo. S tem smo ugotovili, da je podjetje X v svoji panogi in regiji konkurenčno ostalim. Po konkurenčni je sledila še tržna analiza, ki je pokazala, da podjetje X kljub svoji mikro obliki, posluje uspešno. V nadaljevanju smo za podjetje X s pomočjo intervjuja povzeli dosedanjo generično in diverzificirano rast, nato pa zapisali nadaljnje potencialne strateške možnosti. Strateške možnosti smo ocenili na podlagi različnih vidikov in izbrali tri najboljše, ki bi jih podjetje X lahko implementiralo v prihodnje. Magistrsko delo smo zaključili z napotki za implementacijo teh strategij. Podjetju X bomo z izdelavo magistrske naloge pomagali pri ustvarjanju novih strateških možnosti za razširitev poslovanja in nadaljnjo rast.
Ključne besede: rast podjetja, strategije rasti, generična rast, diverzificirana rast, strateške možnosti
Objavljeno v DKUM: 22.04.2024; Ogledov: 58; Prenosov: 12
.pdf Celotno besedilo (1,91 MB)

6.
Treatment of vulvar cancer recurrences with electrochemotherapy : a detailed analysis of possible causes for unsuccessful treatment
Gregor Vivod, Tanja Jesenko, Gorana Gašljević, Nina Kovačević, Maša Omerzel, Gregor Serša, Sebastjan Merlo, Maja Čemažar, 2023, izvirni znanstveni članek

Opis: Background. Electrochemotherapy has good local effectiveness in the treatment of vulvar cancer. Most studies have reported the safety and effectiveness of electrochemotherapy for palliative treatment of gynecological cancers and mostly vulvar squamous cell carcinoma. Some tumors, however, fail to respond to electrochemotherapy. The biological features/determinants for the nonresponsiveness are not determined yet. Patient and methods. A recurrence of vulvar squamous cell carcinoma was treated by electrochemotherapy using intravenous administration of bleomycin. The treatment was performed by hexagonal electrodes according to standard operating procedures. We analyzed the factors that could determine nonresponsiveness to electrochemotherapy. Results. Based on the presented case of nonresponsive vulvar recurrence to electrochemotherapy, we hypothesize that the vasculature of the tumors prior to treatment may predict the response to electrochemotherapy. The histological analysis showed minimal presence of blood vessels in the tumor. Thus, low perfusion may reduce drug delivery and lead to a lower response rate because of the minor antitumor effectiveness of vascular disruption. In this case, no immune response in the tumor was elicited by electrochemotherapy. Conclusions. In this case, of nonresponsive vulvar recurrence treated by electrochemotherapy, we analyzed possible factors that could predict treatment failure. Based on histological analysis, low vascularization of the tumor was observed, which hampered drug delivery and distribution and resulted in no vascular disrupting action of electrochemotherapy. All these factors could contribute to ineffective treatment with electrochemotherapy.
Ključne besede: electrochemotherapy, bleomycin, vulvar cancer
Objavljeno v DKUM: 17.04.2024; Ogledov: 104; Prenosov: 4
.pdf Celotno besedilo (1,45 MB)
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7.
Fatal Hymenoptera Venom–triggered anaphylaxis in patients with unrecognized clonal mast cell disorder : Is mastocytosis to blame?
Matija Rijavec, Jezerka Inkret, Urška Bidovec, Tanja Carli, Nina Frelih, Andreja Kukec, Peter Korošec, Mitja Košnik, 2023, izvirni znanstveni članek

Opis: Hymenoptera venom–triggered anaphylaxis (HVA) affects up to 8.9% of the general population and is the most frequent cause of anaphylaxis in adults, accounting for approximately 20% of all fatal anaphylaxis cases. Quite often, a fatal reaction is a victim’s first manifestation of HVA. Mastocytosis represents one of the most important risk factors for severe HVA. We analyzed patients with documented fatal HVA for the presence of underlying clonal mast cell disorder (cMCD). Here, we report three cases of fatal HVA, with undiagnosed underlying cMCD identified by the presence of the peripheral blood and/or bone marrow KIT p.D816V missense variant postmortem. In the first case, anaphylaxis was the initial episode and was fatal. In the other two cases, both patients were treated with specific venom immunotherapy (VIT), nevertheless, one died of HVA after VIT discontinuation, and the other during VIT; both patients had cardiovascular comorbidities and were taking beta-blockers and/or ACE inhibitors. Our results point to the importance of screening all high-risk individuals for underlying cMCD using highly sensitive molecular methods for peripheral blood KIT p.D816V variant detection, including severe HVA and possibly beekeepers, for proper management and the need for lifelong VIT to prevent unnecessary deaths. Patients at the highest risk of fatal HVA, with concomitant cardiovascular and cMCD comorbidities, might not be protected from field stings even during regular VIT. Therefore, two adrenaline autoinjectors and lifelong VIT, and possibly cotreatment with omalizumab, should be considered for high-risk patients to prevent fatal HVA episodes.
Ključne besede: fatal anaphylaxis, Hymenoptera venom, mastocytosis, venom immunotherapy
Objavljeno v DKUM: 16.04.2024; Ogledov: 72; Prenosov: 0
.pdf Celotno besedilo (717,90 KB)
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8.
Surgical treatment of acute patellar dislocation associated with bony avulsion in children
Samo K. Fokter, Andraž Dovnik, Nina Fokter Dovnik, 2013, izvirni znanstveni članek

Opis: Purpose: The management of acute patellar dislocation in children and adolescents is controversial. Traditionally,most first time traumatic patellar dislocations have been treated nonoperatively. However, due to new knowledge about medial patellar stabilizers some authors have advocated for surgical repair. The present report describes the midterm subjective and functional results of operative treatment of acute patellar dislocation in children less than eighteen years of age with concomitant osteochondral fracture. Methods: Data on a cohort of sixteen patients (eight girls and eight boys) aged 14.9 years (mean, range12-17 years) with acute patellar dislocation were retrospectively collected. Intraarticular fragments were detected in all patients in conventional radiographs. Operative treatment consisted of arthroscopic removal (12cases) or refixation (4 cases) of the osteochondral fragments and direct repair of the damaged medial patellofemoral ligament (MPFL) if that was still feasible (13 cases). All patients were seen at six months, and a telephone interview with twelve patients (75%) was conductedat four years (mean, range 27 years). Results: Of the sixteen patients, two (12.5%) had a recurrent patellar luxation. The subjective IKDC score at the time of the most recent follow up was 86 (mean, range 63-100), and the Marx Activity Rating Scale score was 9.2 (mean, range 216).Conclusions: Direct surgical repair of the injured MPFLmay be considered an option to prevent subsequent dislocation and subluxation in first time traumatic dislocation of the patella in children and adolescents with osteochondral fractures and substantial disruption of medial patellar stabilizers.
Ključne besede: akutni izpah pogačice, patelofemoralna kostna avulzija, izpah pri otrocih, pediatrične poškodbe, kirurško zdravljenje
Objavljeno v DKUM: 12.04.2024; Ogledov: 66; Prenosov: 0
.pdf Celotno besedilo (457,50 KB)
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9.
Male reproductive organ weight : criteria for detection of androstenone-positive carcasses in immunocastrated and antire male pigs
Gregor Fazarinc, Nina Batorek Lukač, Martin Škrlep, Klavdija Poklukar Žnidaršič, Alice Broeke, Kevin Kress, Etienne Labussière, Volker Stefanski, Milka Vrecl, Marjeta Čandek-Potokar, 2023, izvirni znanstveni članek

Opis: Immunocastration and rearing of entire males (EMs) are sustainable alternatives to surgical castration. However, these animal carcasses have variable risk of boar taint and should be identified at the slaughter line. We aimed to identify a simple and reliable indicator of androstenone-related boar taint by evaluating pelvic urogenital tract weight as a marker of boar-taint animals at the slaughter line. The pelvic urogenital tract, testes, and accessory sex glands of EMs and immunocastrates (ICs) were collected, dissected, and weighed, before colorimetric measurements of testicular tissue. Additionally, GnRH antibody titers and testosterone, androstenone, and skatole levels were determined. Our results showed that 81.8% of EMs had androstenone levels above the risk threshold (>0.5 µg/g fat; EM/Ahigh subgroup), whereas in ICs, the C/Ahigh subgroup with androstenone >0.5 µg/g fat accounted for only 4.3%. Androstenone levels correlated negatively with GnRH antibody titers and positively with testosterone levels and reproductive organ weights. Identification of ICs with androstenone levels above the threshold (IC/Ahigh subgroup) may be achieved via testes or pelvic urogenital tract weight measurements. However, in EMs, the latter is a more reliable parameter. A principal component analysis based on these variables and hierarchical clustering also distinguished the Ahigh from the Alow subgroup, irrespective of IC/EM. The findings highlight the possible use of pelvic urogenital tract weight along with testes weight as a simple, reliable, and efficient morphometric indicator for identifying androstenone-positive carcasses of different sex categories.
Ključne besede: boar taint, morphometric indicators, immunocastration, entire males
Objavljeno v DKUM: 11.04.2024; Ogledov: 112; Prenosov: 4
.pdf Celotno besedilo (663,86 KB)
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10.
Decoding firings of a large population of human motor units from high-density surface electromyogram in response to transcranial magnetic stimulation
Jakob Škarabot, Claudia Ammann, Thomas G. Balshaw, Matjaž Divjak, Filip Urh, Nina Murks, Guglielmo Foffani, Aleš Holobar, 2023, izvirni znanstveni članek

Opis: We describe a novel application of methodology for high-density surface electromyography (HDsEMG) decomposition to identify motor unit (MU) firings in response to transcranial magnetic stimulation (TMS). The method is based on the MU filter estimation from HDsEMG decomposition with convolution kernel compensation during voluntary isometric contractions and its application to contractions elicited by TMS. First, we simulated synthetic HDsEMG signals during voluntary contractions followed by simulated motor evoked potentials (MEPs) recruiting an increasing proportion of the motor pool. The estimation of MU filters from voluntary contractions and their application to elicited contractions resulted in high (>90%) precision and sensitivity of MU firings during MEPs. Subsequently, we conducted three experiments in humans. From HDsEMG recordings in first dorsal interosseous and tibialis anterior muscles, we demonstrated an increase in the number of identified MUs during MEPs evoked with increasing stimulation intensity, low variability in the MU firing latency and a proportion of MEP energy accounted for by decomposition similar to voluntary contractions. A negative relationship between the MU recruitment threshold and the number of identified MU firings was exhibited during the MEP recruitment curve, suggesting orderly MU recruitment. During isometric dorsiflexion we also showed a negative association between voluntary MU firing rate and the number of firings of the identified MUs during MEPs, suggesting a decrease in the probability of MU firing during MEPs with increased background MU firing rate. We demonstrate accurate identification of a large population of MU firings in a broad recruitment range in response to TMS via non-invasive HDsEMG recordings. KEY POINTS: Transcranial magnetic stimulation (TMS) of the scalp produces multiple descending volleys, exciting motor pools in a diffuse manner. The characteristics of a motor pool response to TMS have been previously investigated with intramuscular electromyography (EMG), but this is limited in its capacity to detect many motor units (MUs) that constitute a motor evoked potential (MEP) in response to TMS. By simulating synthetic signals with known MU firing patterns, and recording high-density EMG signals from two human muscles, we show the feasibility of identifying firings of many MUs that comprise a MEP. We demonstrate the identification of firings of a large population of MUs in the broad recruitment range, up to maximal MEP amplitude, with fewer required stimuli compared to intramuscular EMG recordings. The methodology demonstrates an emerging possibility to study responses to TMS on a level of individual MUs in a non-invasive manner.
Ključne besede: transcranial magnetic stimulation, TMS, electromyiograms
Objavljeno v DKUM: 10.04.2024; Ogledov: 297; Prenosov: 1
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