1. Protokol za klinično kirurško tutorstvo : gradivo za študente medicine in študente tutorje2025 Opis: Protokol za kirurško tutorstvo je izdelek, ki je od ideje do izdaje nastajal tekom študijskih let zdajšnjih diplomantov Medicinske fakultete Univerze v Mariboru, mladih.zdravnikov. Gradivo zajema teme od pojasnilne dolžnosti do alternativkirurškega šivanja, vključujoč osnove obnašanja v operacijski dvorani, predstavitev kirurških instrumentov, antiseptične priprave sterilnega polja, sivi in vozlanje. Koraki posameznih protokolov so zapisani po točkah, tekst pa spremljajo ilustracije kolegice, ravno tako diplomantke MF UM, mlade zdravnice. Gradivo je plod truda in usklajevanja kolegov in mentorjev; vsi, ki smo pri skripti sodelovali upamo, da bo sluzila svojemu namenu.
Ključne besede: kirurgija, šivanje, protokoli, instrumenti, veščine, tutorstvo
Objavljeno v DKUM: 24.10.2025; Ogledov: 0; Prenosov: 2
 Celotno besedilo (2,71 MB)
Gradivo ima več datotek! Več... |
2. Mesenchymal stem cells isolated from paediatric paravertebral adipose tissue show strong osteogenic potentialJan Rožanc, Lidija Gradišnik, Tomaž Velnar, Minja Gregorič, Marko Milojević, Boštjan Vihar, Boris Gole, Uroš Maver, 2022, izvirni znanstveni članek Opis: Mesenchymal stem cells (MSCs) represent the basis of novel clinical concepts in cellular therapy and tissue regeneration. Therefore, the isolation of MSCs from various tissues has become an important endeavour for stem cell biobanking and the development of regenerative therapies. Paravertebral adipose tissue is readily exposed during spinal procedures in children and could be a viable source of stem cells for therapeutic applications. Here, we describe the first case of MSCs isolated from paravertebral adipose tissue (PV-ADMSCs), obtained during a routine spinal surgery on a child. Using quantitative real-time PCR and flow cytometry, we show that PV-ADMSCs have different levels of stem marker expression compared to the MSCs from other sources while having the highest proliferation rate. Furthermore, we evaluate the multipotency of PV-ADMSCs by the three-lineage (adipogenic, osteogenic and chondrogenic) differentiation and compare it to the multipotency of MSCs from other sources. It was found that the PV-ADMSCs have a strong osteogenic potential in particular. Taken together, our data indicate that PV-ADMSCs meet the criteria for successful cell therapy, defined by the International Society for Cellular Therapy (ISCT), and thus, could provide a source of MSCs that is relatively easy to isolate and expand in culture. Due to their strong osteogenic potential, these cells provide a promising basis, especially for orthopaedic applications.
Ključne besede: mesenchymal stem cells, paediatric surgery, paravertebral adipose tissue, regenerative medicine, stem marker expression, osteogenic potential, differentiation
Objavljeno v DKUM: 16.12.2024; Ogledov: 0; Prenosov: 13
Celotno besedilo (3,70 MB)
Gradivo ima več datotek! Več... |
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