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Opis: Urednik Marko Jesenšek je pripravil vrhunsko znanstveno delo s področja slovenskega slovaropisja. V monografiji, ki ima 20 samostojnih poglavij, so predstavljeni najnovejši dosežki na področju eSSKJ-a, Slovarja pregovorov in sorodnih paremioloških izrazov, Sprotnega slovarja slovenskega jezika, Rastočega besednjaka SLA, Slovarja slovenskega taroka, jezikovne terminologije v Pleteršnikovem slovarju in njegove makronske dediščine, analize Pleteršnikove rokopisne zbirke zemljepisnih imen in številnih drugih pomembnih ozko slovaropisnih vprašanj s področja sinhronije in diahronije. Pri pisanju so sodelovali najbolj aktivni slovenski jezikoslovci, ki se na Slovenski akademiji znanosti in umetnosti, na ZRC SAZU, na Univerzi v Ljubljani in Univerzi v Mariboru ukvarjajo s slovenskim slovaropisjem ter življenjem in delom Maksa Pleteršnika. Znanstvena monografija Pleteršnikova dediščina je nastala ob stoletnici smrti znamenitega slovaropisca Maksa Pleteršnika (* 3. 12. 1840, Pišece, † 13. 9. 1923, Pišece). Gre za inovativno, aktualno in doslej najpopolnejše delo s področja slovaropisja, ki promovira slovensko jezikoslovno znanost in razširja vedenje o slovenski kulturni in jezikoslovni dediščini.
Ključne besede: Maks Pleteršnik, slovenski jezik, slovaropisje, slovarji, jezikovni viri in tehnologije
Objavljeno v DKUM: 04.09.2024; Ogledov: 71; Prenosov: 6
Celotno besedilo (6,39 MB)
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Opis: Type 2 diabetes mellitus (T2DM) has been associated with insulin resistance and the failure of β-cells to produce and secrete enough insulin as the disease progresses. However, clinical treatments based solely on insulin secretion and action have had limited success. The focus is therefore shifting towards α-cells, in particular to the dysregulated secretion of glucagon. Our qualitative electron-microscopy-based observations gave an indication that mitochondria in α-cells are altered in Western-diet-induced T2DM. In particular, α-cells extracted from mouse pancreatic tissue showed a lower density of mitochondria, a less expressed matrix and a lower number of cristae. These deformities in mitochondrial ultrastructure imply a decreased efficiency in mitochondrial ATP production, which prompted us to theoretically explore and clarify one of the most challenging problems associated with T2DM, namely the lack of glucagon secretion in hypoglycaemia and its oversecretion at high blood glucose concentrations. To this purpose, we constructed a novel computational model that links α-cell metabolism with their electrical activity and glucagon secretion. Our results show that defective mitochondrial metabolism in α-cells can account for dysregulated glucagon secretion in T2DM, thus improving our understanding of T2DM pathophysiology and indicating possibilities for new clinical treatments.
Ključne besede: diabetes, pancreatic alpha cells, glucagon, mitochondrial dysfunction, free fatty acid
Objavljeno v DKUM: 03.09.2024; Ogledov: 44; Prenosov: 2
Celotno besedilo (1,60 MB)
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Opis: Namen magistrskega dela je predstaviti teoretične okvirje in pravilnike za področje vodenja in zavarovanja prometa v času gradnje in za postavitev cestnih zapor. Predstavili smo slovensko zakonodajo na področju cestnih zapor pa tudi primere iz tujine ter evropsko regulativo. Opisali smo programe, ki so se uporabljali za izdelavo elaborata. V praktičnem delu smo predstavili izdelavo zahtevnejšega elaborata vodenja in zavarovanja prometa v času gradnje na primeru protipoplavne ureditve Selške Sore. Elaborat služi za pridobitev stroškovne ocene in za preveritev izvedbe gradnje. Obravnavi projekt je bil v času pisanja magistrske naloge že v izvajanju, zato smo lahko primerjali izdelano projektno dokumentacijo z izvedenim stanjem na terenu- Prikazali smo tudi fotografije s terena v času izvedbe gradbenih del. Ugotovljeno je bilo, da se sama izvedba zapore na terenu razlikuje od predvidene v izdelanem elaboratu.
Ključne besede: elaborat, vodenje in zavarovanje prometa v času gradnje, prometna zapora, tipske sheme zapor
Objavljeno v DKUM: 30.08.2024; Ogledov: 73; Prenosov: 9
Celotno besedilo (4,99 MB)

Opis: This in-depth study explores the intricate dynamics of reflective materials, emphasizing their impact on the indoor thermal environment and urban heat island (UHI) mitigation. Examining diffuse highly reflective (DHR), general reflective (GR), and retro-reflective (RR) materials on a simplified building model during summer days, the research utilizes outdoor experiments to analyze air and surface temperatures, as well as solar radiation. Prioritizing key metrics—mean radiant temperature (MRT), operative temperature (OT), and solar reflectance (ρ)—the study uncovers nuanced distinctions in DHR, GR, and RR materials. Solar reflectance calculations consistently show higher values for DHR and RR materials compared to GR material, highlighting reflectance's pivotal role in influencing surface temperatures and indoor thermal environment. When evaluating the impact of exterior wall materials on building temperatures, RR material with a 76% reflectance performs similarly to DHR material (82%). Notably, with a 6% lower reflectance in RR, the temperature contrast between external and internal walls is only about 1.5 °C at its maximum, underscoring RR's effectiveness as an outer wall material for UHI mitigation and building energy conservation, surpassing both DHR and GR materials.
Ključne besede: urban heat island, reflective materials, indoor thermal environment, solar reflectance, simplified building model
Objavljeno v DKUM: 23.08.2024; Ogledov: 106; Prenosov: 3
Celotno besedilo (4,82 MB)

Opis: Social distancing is an efective strategy to mitigate the impact of infectious diseases. If sick or healthy, or both, predominantly socially distance, the epidemic curve fattens. Contact reductions may occur for diferent reasons during a pandemic including health-related mobility loss (severity of symptoms), duty of care for a member of a high-risk group, and forced quarantine. Other decisions to reduce contacts are of a more voluntary nature. In particular, sick people reduce contacts consciously to avoid infecting others, and healthy individuals reduce contacts in order to stay healthy. We use game theory to formalize the interaction of voluntary social distancing in a partially infected population. This improves the behavioral micro-foundations of epidemiological models, and predicts diferential social distancing rates dependent on health status. The model's key predictions in terms of comparative statics are derived, which concern changes and interactions between social distancing behaviors of sick and healthy. We ft the relevant parameters for endogenous social distancing to an epidemiological model with evidence from infuenza waves to provide a benchmark for an epidemic curve with endogenous social distancing. Our results suggest that spreading similar in peak and case numbers to what partial immobilization of the population produces, yet quicker to pass, could occur endogenously. Going forward, eventual social distancing orders and lockdown policies should be benchmarked against more realistic epidemic models that take endogenous social distancing into account, rather than be driven by static, and therefore unrealistic, estimates for social mixing that intrinsically overestimate spreading.
Ključne besede: COVID-19, pandemic, disease dynamics, exponential growth, virality
Objavljeno v DKUM: 14.08.2024; Ogledov: 120; Prenosov: 3
Celotno besedilo (1,88 MB)
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