1. Notranji nadzor pitne vode v zdravstveni ustanovi in načrt ukrepanja ob izrednih dogodkih : magistrsko deloGoran Novak, 2025, magistrsko delo Opis: V magistrskem delu sta obravnavana notranji nadzor pitne vode v zdravstveni ustanovi in načrt ukrepanja ob izrednih dogodkih. Namen raziskave je bil ugotoviti delež zdravstvene ustreznosti in skladnosti pitne vode v interni vodovodni napeljavi javnega zdravstvenega zavoda Univerzitetni klinični center Maribor, raziskati učinkovitost letnega načrta spremljanja zdravstvene ustreznosti in skladnosti pitne vode ter primerjati zdravstveno ustreznost in skladnost pitne vode med lokacijo Maribor in lokacijo Slivniško Pohorje. Uporabljene metode so vključevale vzorčenje in laboratorijsko preskušanje pitne vode na parametre iz Uredbe o pitni vodi. Magistrsko delo temelji na rezultatih mikrobiološkega preskušanja pitne vode, odvzetih vzorcih v času med 1. januarjem 2013 in 31. decembrom 2021. Skupno je bilo analiziranih 1.642 vzorcev pitne vode, od katerih je bilo 95,2 % skladnih z mejnimi vrednostmi parametrov iz Uredbe o pitni vodi. Delež zdravstvene ustreznosti in skladnosti pitne vode, vzorčenih na interni vodovodni napeljavi zdravstvenih objektov UKC Maribor na lokaciji Maribor, je bil višji kot delež zdravstvene ustreznosti in skladnosti pitne vode, vzorčenih na interni vodovodni napeljavi zdravstvenega objekta UKC Maribor na lokaciji Slivniško Pohorje. Ugotovljeno je, da dosledno izvajanje preventivnih in korekcijskih ukrepov bistveno pripomore k izboljšanju zdravstvene ustreznosti in skladnosti pitne vode. S tem magistrskim delom je omogočen hitrejši vpogled nad obvladovanjem bolnišničnih okužb s področja oskrbe z zdravstveno ustrezno pitno vodo. V prihodnje je priporočeno dosledno izvajanje notranjega nadzora in preventivnih ukrepov za zagotavljanje zdravstveno ustrezne in skladne pitne vode, redno posodabljanje načrta ukrepanja ob izrednih dogodkih ter izobraževanja osebja glede pomena zagotavljanja ustrezne kakovosti pitne vode.
Ključne besede: pitna voda, notranji nadzor, zdravstvena ustreznost, načrt ukrepanja ob izrednih dogodkih, interna vodovodna napeljava
Objavljeno v DKUM: 05.05.2025; Ogledov: 0; Prenosov: 8
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2. Expressing added value in food supply chainsNejc Zidar, Jernej Turk, Jernej Prišenk, 2023, izvirni znanstveni članek Opis: Value-added food supply chains are chains that maintain positive social, environmental, and community values which are integrated into the production process from the primary producer to the final consumer, ensuring economic, social, and environmental sustainability, thus forming a sustainable agricultural and food production system. The evaluation of the value added in each chain is based on indicators, which are a tool to measure changes in the actual situation or to show performance trends in achieving the progress set by the objectives. The presented indicators are based on publicly available statistics and foreign literature that allow measuring value added in specific livestock chains at aggregate level (beef production, pork production and dairy production) and are based on publicly available statistics in the Republic of Slovenia. The need to produce indicators of value added in livestock food supply chains arises from the large differences in structural changes in the sector itself and in the development and economic performance of the various livestock industries.
Ključne besede: food supply chain, value-added, indicators, sustainability, economic, social and environmental aspect
Objavljeno v DKUM: 23.04.2025; Ogledov: 0; Prenosov: 2
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5. Ranking as a procedure for selecting a replacement variable in the score predicting the survival of patients treated with curative intent for colorectal liver metastasesIrena Plahuta, Matej Mencinger, Iztok Peruš, Tomislav Magdalenić, Špela Turk, Aleks Brumec, Stojan Potrč, Arpad Ivanecz, 2023, izvirni znanstveni članek Opis: Background and Objectives: The issue of a missing variable precludes the external validation of many prognostic models. For example, the Liverpool score predicts the survival of patients undergoing surgical therapy for colorectal liver metastases, but it includes the neutrophil–lymphocyte ratio, which cannot be measured retrospectively.
Materials and Methods: We aimed to find the most appropriate replacement for the neutrophil–lymphocyte ratio. Survival analysis was performed on data representing 632 liver resections for colorectal liver metastases from 2000 to 2020. Variables associated with the Liverpool score, C-reactive protein, albumins, and fibrinogen were ranked. The rankings were performed in four ways: The first two were based on the Kaplan-Meier method (log-rank statistics and the definite integral ��
between two survival curves). The next method of ranking was based on univariate and multivariate Cox regression analyses.
Results: The ranks were as follows: the radicality of liver resection (rank 1), lymph node infiltration of primary colorectal cancer (rank 2), elevated C-reactive protein (rank 3), the American Society of Anesthesiologists Classification grade (rank 4), the right-sidedness of primary colorectal cancer (rank 5), the multiplicity of colorectal liver metastases (rank 6), the size of colorectal liver metastases (rank 7), albumins (rank 8), and fibrinogen (rank 9).
Conclusions: The ranking methodologies resulted in almost the same ranking order of the variables. Elevated C-reactive protein was ranked highly and can be considered a relevant replacement for the neutrophil–lymphocyte ratio in the Liverpool score. These methods are suitable for ranking variables in similar models for medical research.
Ključne besede: colorectal cancer, liver metastases, inflammation, ranking, survival
Objavljeno v DKUM: 07.04.2025; Ogledov: 0; Prenosov: 4
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6. The learning curve of laparoscopic liver resection utilising a difficulty scoreArpad Ivanecz, Irena Plahuta, Matej Mencinger, Iztok Peruš, Tomislav Magdalenić, Špela Turk, Stojan Potrč, 2022, izvirni znanstveni članek Opis: Background: This study aimed to quantitatively evaluate the learning curve of laparoscopic liver resection (LLR) of a single surgeon.
Patients and methods: A retrospective review of a prospectively maintained database of liver resections was conducted. 171 patients undergoing pure LLRs between April 2008 and April 2021 were analysed. The Halls difficulty score (HDS) for theoretical predictions of intraoperative complications (IOC) during LLR was applied. IOC was defined as blood loss over 775 mL, unintentional damage to the surrounding structures, and conversion to an open approach. Theoretical association between HDS and the predicted probability of IOC was utilised to objectify the shape of the learning curve.
Results: The obtained learning curve has resulted from thirteen years of surgical effort of a single surgeon. It consists of an absolute and a relative part in the mathematical description of the additive function described by the logarithmic function (absolute complexity) and fifth-degree regression curve (relative complexity). The obtained learning curve determines the functional dependency of the learning outcome versus time and indicates several local extreme values (peaks and valleys) in the learning process until proficiency is achieved.
Conclusions: This learning curve indicates an ongoing learning process for LLR. The proposed mathematical model can be applied for any surgical procedure with an existing difficulty score and a known theoretically predicted association between the difficulty score and given outcome (for example, IOC).
Ključne besede: difficulty score, learning curve, laparoscopy, hepatectomy, intraoperative complications, surgical procedures
Objavljeno v DKUM: 07.04.2025; Ogledov: 0; Prenosov: 2
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7. Sweet, fat and salty: snacks in vending machines in health and social care institutions in SloveniaUrška Rozman, Igor Pravst, Urška Pivk Kupirovič, Urška Blaznik, Primož Kocbek, Sonja Šostar-Turk, 2020, izvirni znanstveni članek Opis: Vending machines in health and social care facilities are often the only possible choice for a quick snack for workers and visitors, in many cases providing unhealthy dietary choices. Our study aimed to analyse the variety and nutritional quality of foods available in vending machines placed in social and health care institution in Slovenia. The available snacks were quantitatively assessed, using traffic light profiling. The model used for nutrient profiling was that of the Food Standards Australia New Zealand (FSANZ). Vending machines in 188 institutions were surveyed, resulting in 5625 food-items consisting of 267 unique product labels. Sweet products dominate in vending machines offers (about 70%), while nuts and seeds (8.4%), yoghurts (2.1%), fruits (1.4%) and milk (0.3%) are present in a very small proportion or are not available at all. According to FSANZ, 88.5% of all displayed food items in vending machines can be considered as lower nutritional quality or less healthy products. The authors’ future activities will be focused on ensuring wider availability of healthy dietary choices and on including official guidelines in tender conditions for vending machines in health and social care institutions in Slovenia.
Ključne besede: snacks, vending machines, social care institutions, health care institutions, Slovenia
Objavljeno v DKUM: 10.03.2025; Ogledov: 0; Prenosov: 9
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8. Kultura varnosti pri delu v operacijskih dvoranahTeodor Pevec, 2025, doktorska disertacija Opis: Izhodišča in namen raziskave: Bolnikova varnost je postala glavna skrb izvajalcev in kreatorjev zdravstvenega sistema, saj se v Evropi varnostni zapleti zgodijo pri 8 % do 12 % vseh sprejetih bolnikov v bolnišnice.
Metode: Razvili smo slovenski vprašalnik odnosa do varnosti v operacijskih dvoranah in na
istem vzorcu zaposlenih v operacijskih dvoranah v sedmih od deset slovenskih regionalnih bolnišnicah ugotavljali vpliv poklicne skupine in izkušenj na odnos do varnosti. Nadaljevali smo s kvalitativno raziskavo, kjer smo pri predstavnikih poklicnih skupin, ki delajo v operacijskih dvoranah, ugotavljali odnos do incidentne situacije. Na koncu pa preverili, kako se upoštevajo priporočila za uporabo preventivne antibiotične zaščite.
Rezultati: Slovenska verzija vprašalnika odnosa do varnosti v operacijski dvorani vsebuje 28 vprašanj in izkazuje primerne kriterije veljavnosti in zanesljivosti. Pri reševanju incidentov ne pride do pomoči med različnimi profili zaposlenih v operacijski dvorani. Vsi elementi perioperativne antibiotične zaščite so bili pravilno upoštevani pri 82 % bolnikov.
Zaključek: Slovenski vprašalnik o varnostni kulturi v operacijskih dvoranah je dober merilni instrument, in se lahko uporablja tako pri opredelitvi potencialno nevarnih področij za varnost bolnikov kakor za merjenje učinka ukrepov za povečanje kulture varnosti.
Ključne besede: kultura varnosti, vprašalnik, raziskava mešanega tipa, perioperativna antibiotična zaščita
Objavljeno v DKUM: 18.02.2025; Ogledov: 0; Prenosov: 27
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9. Spolni stereotipi, povezani s športom, med otroki in mladostniki : magistrsko deloNives Turk, Karolina Vӧrӧš, 2024, magistrsko delo Opis: Spolni stereotipi so prepričanja o tem, kaj velja za moški spol in kaj za ženski spol, zajemajo zunanji izgled, stališča, interese, psihološke značilnosti, družbene odnose in poklice. Začnejo se oblikovati zelo zgodaj v otroštvu in vplivajo na samopodobo ter samozavest posameznika, dolgoročno lahko vplivajo na njihove izobraževalne in karierne poti. Namen magistrskega dela je bil raziskati spolne stereotipe v športu, med otroci in mladostniki, s pomočjo anketnih vprašalnikov in s statistično analizo pridobljenih podatkov. Raziskovalni vzorec obsega 819 učencev, od 3. do 9. razreda, naključno izbranih osnovnih šol (389 ženskega in 428 moškega spola, 2 nista označila) ter 253 dijakov (181 ženskega in 66 moškega spola) naključno izbranih srednjih šol. Rezultati so pokazali, da učenci večino športov dojemajo kot tipično moških, z izjemo izrazito tipično ženskih športov (ples, ritmična gimnastika, umetnostno drsanje in sinhrono plavanje), pri dijakih se dojemanje športov kot tipično moških oz. tipično ženskih nekoliko zmanjša. Ženski del vseh anketiranih ocenjuje športe nekoliko bolj spolno nevtralne kot moški. Delež udejstvovanja v tekmovalnih športih se v višjih razredih osnovne šole in pri dijakih drastično zmanjša. Rezultati so pokazali tudi, da udeleženci, ki se ukvarjajo s tekmovalnim športom in spremljajo športne medije, kot svojo navdihujočo osebo pogosteje navajajo športnika/-co v primerjavi s tistimi, ki niso aktivni v športu.
Ključne besede: šport, stereotipi, spolna identiteta, vzgojno-izobraževalno obdobje
Objavljeno v DKUM: 13.02.2025; Ogledov: 0; Prenosov: 13
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10. Effect of Lactobacillus spp. on adhesion, invasion, and translocation of Campylobacter jejuni in chicken and pig small-intestinal epithelial cell linesMaja Šikić Pogačar, Tomaž Langerholc, Dušanka Mičetić-Turk, Sonja Smole Možina, Anja Klančnik, 2020, izvirni znanstveni članek Opis: Background : Campylobacter spp. are a major cause of bacterial food-borne diarrhoeal disease. This mainly arises through contamination of meat products during processing. For infection, Campylobacter spp. must adhere to epithelial cells of the mucus layer, survive conditions of the gastrointestinal tract, and colonise the intestine of the host. Addition of probiotic bacteria might promote competitive a dhesion to epithelial cells, consequently reducing Campylobacter jejuni colonisation. Effect of Lactobacillus spp. (PCS20, PCS22, PCS25, LGG, PCK9) on C. jejuni adhesion, invasion and translocation in pig (PSI cl.1) and chicken (B1OXI) small-intestine cell lines, as well as pig enterocytes (CLAB) was investigated.
Results : Overall, in competitive adhesion assays with PSI cl.1 and CLAB cell monolayers, the addition of Lactobacillus spp. reduced C. jejuni adherence to the cell surface, and negatively affected the C. jejuni invasion. Interestingly, Lactobacillus spp. significantly impaired C. jejuni adhesion in three-dimensional functional PSI cl.1 and B1OXI cell models. Also, C. jejuni did not translocate across PSI cl.1 and B1OXI cell monolayers when co-incubated with probiotics. Among selected probiotics, Lactobacillus rhamnosus LGG was the strain that reduced adhesion efficacy of C. jejuni most significantly under co-culture conditions.
Conclusion : The addition of Lactobacillus spp. to feed additives in livestock nutrition might be an effective novel strategy that targets Campylobacter adhesion to epithelial cells, and thus prevents colonisation, reduces the transmission, and finally lowers the incidence of human campylobacteriosis.
Ključne besede: Campylobacter jejuni, Lactobacillus spp., chicken and pig cell line, adhesion, invasion, translocation
Objavljeno v DKUM: 06.02.2025; Ogledov: 0; Prenosov: 2
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