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1.
Microvascular tissue engineering : a review
Jernej Vajda, Marko Milojević, Uroš Maver, Boštjan Vihar, 2021, review article

Abstract: Tissue engineering and regenerative medicine have come a long way in recent decades, but the lack of functioning vasculature is still a major obstacle preventing the development of thicker, physiologically relevant tissue constructs. A large part of this obstacle lies in the development of the vessels on a microscale%the microvasculature%that are crucial for oxygen and nutrient delivery. In this review, we present the state of the art in the field of microvascular tissue engineering and demonstrate the challenges for future research in various sections of the field. Finally, we illustrate the potential strategies for addressing some of those challenges.
Keywords: regenerative medicine, tissue engineering, vascularization, biomaterials, microvascularization, coculture, gradients
Published in DKUM: 18.10.2024; Views: 0; Downloads: 4
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2.
Advanced bio-based polymers for astrocyte cell models
Lidija Gradišnik, Roman Bošnjak, Tina Maver, Tomaž Velnar, 2021, review article

Abstract: The development of in vitro neural tissue analogs is of great interest for many biomedical engineering applications, including the tissue engineering of neural interfaces, treatment of neurodegenerative diseases, and in vitro evaluation of cell-material interactions. Since astrocytes play a crucial role in the regenerative processes of the central nervous system, the development of biomaterials that interact favorably with astrocytes is of great research interest. The sources of human astrocytes, suitable natural biomaterials, guidance scaffolds, and ligand patterned surfaces are discussed in the article. New findings in this field are essential for the future treatment of spinal cord and brain injuries.
Keywords: astrocytes, hydrogels, tissue engineering
Published in DKUM: 14.08.2024; Views: 118; Downloads: 8
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