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1.
Local and global stimuli in reinforcement learning
Danyang Jia, Hao Guo, Zhao Song, Lei Shi, Xinyang Deng, Matjaž Perc, Zhen Wang, 2021, original scientific article

Abstract: In efforts to resolve social dilemmas, reinforcement learning is an alternative to imitation and exploration in evolutionary game theory. While imitation and exploration rely on the performance of neighbors, in reinforcement learning individuals alter their strategies based on their own performance in the past. For example, according to the Bush-Mosteller model of reinforcement learning, an individual's strategy choice is driven by whether the received payoff satisfies a preset aspiration or not. Stimuli also play a key role in reinforcement learning in that they can determine whether a strategy should be kept or not. Here we use the Monte Carlo method to study pattern formation and phase transitions towards cooperation in social dilemmas that are driven by reinforcement learning. We distinguish local and global players according to the source of the stimulus they experience. While global players receive their stimuli from the whole neighborhood, local players focus solely on individual performance. We show that global players play a decisive role in ensuring cooperation, while local players fail in this regard, although both types of players show properties of "moody cooperators". In particular, global players evoke stronger conditional cooperation in their neighborhoods based on direct reciprocity, which is rooted in the emerging spatial patterns and stronger interfaces around cooperative clusters.
Keywords: evolutionary game theory, cooperation, learning, social physics
Published in DKUM: 03.03.2025; Views: 0; Downloads: 0
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2.
The self-organizing impact of averaged payoffs on the evolution of cooperation
Attila Szolnoki, Matjaž Perc, 2021, original scientific article

Abstract: According to the fundamental principle of evolutionary game theory, the more successful strategy in a population should spread. Hence, during a strategy imitation process a player compares its payoff value to the payoff value held by a competing strategy. But this information is not always accurate. To avoid ambiguity a learner may therefore decide to collect a more reliable statistics by averaging the payoff values of its opponents in the neighborhood, and makes a decision afterwards. This simple alteration of the standard microscopic protocol significantly improves the cooperation level in a population. Furthermore, the positive impact can be strengthened by increasing the role of the environment and the size of the evaluation circle. The mechanism that explains this improvement is based on a self-organizing process which reveals the detrimental consequence of defector aggregation that remains partly hidden during face-to-face comparisons. Notably, the reported phenomenon is not limited to lattice populations but remains valid also for systems described by irregular interaction networks.
Keywords: evolutionary game theory, cooperation, learning, social physics
Published in DKUM: 03.03.2025; Views: 0; Downloads: 0
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3.
Optimal governance and implementation of vaccination programmes to contain the COVID-19 pandemic
Mahendra Piraveenan, Shailendra Sawleshwarkar, Michael Walsh, Iryna Zablotska, Samit Bhattacharyya, Habib Hassan Farooqui, Tarun Bhatnagar, Anup Karan, Manoj Murhekar, Sanjay P. Zodpey, K. S. Mallikarjuna Rao, Philippa Pattison, Albert Y. Zomaya, Matjaž Perc, 2021, original scientific article

Abstract: Since the recent introduction of several viable vaccines for SARS-CoV-2, vaccination uptake has become the key factor that will determine our success in containing the COVID-19 pandemic. We argue that game theory and social network models should be used to guide decisions pertaining to vaccination programmes for the best possible results. In the months following the introduction of vaccines, their availability and the human resources needed to run the vaccination programmes have been scarce in many countries. Vaccine hesitancy is also being encountered from some sections of the general public. We emphasize that decision-making under uncertainty and imperfect information, and with only conditionally optimal outcomes, is a unique forte of established game-theoretic modelling. Therefore, we can use this approach to obtain the best framework for modelling and simulating vaccination prioritization and uptake that will be readily available to inform important policy decisions for the optimal control of the COVID-19 pandemic.
Keywords: COVID-19, evolutionary game theory, digital epidemiology, vaccination, social network, public goods game, social physics
Published in DKUM: 28.02.2025; Views: 0; Downloads: 2
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4.
Dissimilarity-driven behavior and cooperation in the spatial public goods game
Yinhai Fang, Tina Perc Benko, Matjaž Perc, Haiyan Xu, 2019, original scientific article

Abstract: In this paper, we explore the impact of four different types of dissimilarity-driven behavior on the evolution of cooperation in the spatial public goods game. While it is commonly assumed that individuals adapt their strategy by imitating one of their more successful neighbors, in reality only very few will be awarded the highest payoffs. Many have equity or equality preferences, and they have to make do with an average or even with a low payoff. To account for this, we divide the population into two categories. One consists of payoff-driven players, while the other consists of dissimilarity-driven players. The later imitate the minority strategy in their group based on four different dissimilaritydriven behaviors. The rule that most effectively promotes cooperation, and this regardless of the multiplication factor of the public goods game, is when individuals adopt the minority strategy only when their payoff is better than that of their neighbors. If the dissimilarity-driven players adopt the minority strategy regardless of the payoffs of others, or if their payoff is the same, the population typically evolves towards a neutral state where cooperators and defectors are equally common. This may be beneficial when the multiplication factor is low, when defectors would otherwise dominate. However, if the dissimilarity-driven players adopt the minority strategy only when their payoff is worse than that of their neighbors, then cooperation is not promoted at all in comparison to the baseline case in the absence of dissimilarity-driven behavior. We explore the pattern formation behind these results, and we discuss their wider implications for the better understanding of cooperative behavior in social groups.
Keywords: theoretical biology, evolution, agent-based modeling, complex system, network science, evolutionary game theory
Published in DKUM: 26.02.2025; Views: 0; Downloads: 3
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5.
Identification of influential invaders in evolutionary populations
Guoli Yang, Tina Perc Benko, Matteo Cavaliere, Jincai Huang, Matjaž Perc, 2019, original scientific article

Abstract: The identification of the most influential nodes has been a vibrant subject of research across the whole of network science. Here we map this problem to structured evolutionary populations, where strategies and the interaction network are both subject to change over time based on social inheritance. We study cooperative communities, which cheaters can invade because they avoid the cost of contributions that are associated with cooperation. The question that we seek to answer is at which nodes cheaters invade most successfully. We propose the weighted degree decomposition to identify and rank the most influential invaders. More specifically, we distinguish two kinds of ranking based on the weighted degree decomposition. We show that a ranking strategy based on negative-weighted degree allows to successfully identify the most influential invaders in the case of weak selection, while a ranking strategy based on positive-weighted degree performs better when the selection is strong. Our research thus reveals how to identify the most influential invaders based on statistical measures in dynamically evolving cooperative communities.
Keywords: theoretical biology, evolution, agent-based modeling, complex system, network science, evolutionary game theory
Published in DKUM: 26.02.2025; Views: 0; Downloads: 2
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6.
Evolutionary dynamics of any multiplayer game on regular graphs
Chaoqian Wang, Matjaž Perc, Attila Szolnoki, 2024, original scientific article

Abstract: Multiplayer games on graphs are at the heart of theoretical descriptions of key evolutionary processes that govern vital social and natural systems. However, a comprehensive theoretical framework for solving multiplayer games with an arbitrary number of strategies on graphs is still missing. Here, we solve this by drawing an analogy with the Balls-and-Boxes problem, based on which we show that the local configuration of multiplayer games on graphs is equivalent to distributing k identical co-players among n distinct strategies. We use this to derive the replicator equation for any n-strategy multiplayer game under weak selection, which can be solved in polynomial time. As an example, we revisit the second-order free-riding problem, where costly punishment cannot truly resolve social dilemmas in a well-mixed population. Yet, in structured populations, we derive an accurate threshold for the punishment strength, beyond which punishment can either lead to the extinction of defection or transform the system into a rock-paper-scissors-like cycle. The analytical solution also qualitatively agrees with the phase diagrams that were previously obtained for non-marginal selection strengths. Our framework thus allows an exploration of any multi-strategy multiplayer game on regular graphs.
Keywords: evolutionary game theory, cooperation, network, social physics
Published in DKUM: 26.02.2025; Views: 0; Downloads: 1
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7.
Exploring antioxidative properties of xanthohumol and isoxanthohumol : an integrated experimental and computational approach with isoxanthohumol pKa determination
Jelena Tošović, Zala Kolenc, Gregor Hostnik, Urban Bren, 2025, original scientific article

Abstract: This study explores the antioxidative activities of xanthohumol (XN) and isoxanthohumol (IXN), prenylated flavonoids from Humulus lupulus (family Cannabaceae), utilizing the oxygen radical absorption capacity (ORAC) and ferric reducing antioxidant power (FRAP) assays along with computational Density Functional Theory methods. Experimentally, XN demonstrated significantly higher antioxidative capacities than IXN. Moreover, we determined IXN pKa values using the UV/Vis spectrophotometric method for the first time, facilitating its accurate computational modeling under physiological conditions. Through a thermodynamic approach, XN was found to efficiently scavenge HOO• and CH3O• radicals via Hydrogen Atom Transfer (HAT) and Radical Adduct Formation (RAF) mechanisms, while CH3OO• scavenging was feasible only through the HAT pathway. IXN exhibited its best antioxidative activity against CH3O• via both HAT and RAF mechanisms and could also scavenge HOO• through RAF. Both Single Electron Transfer (SET) and Sequential Proton Loss-Electron Transfer (SPLET) mechanisms were thermodynamically unfavorable for all radicals and both compounds.
Keywords: antioxidative activity, bio-active membranes, xanthohumol, isoxanthohumol, ORAC and FRAP assays, pKa determination, density functional theory, DFT
Published in DKUM: 31.01.2025; Views: 0; Downloads: 4
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8.
Cooperation on interdependent networks by means of migration and stochastic imitation
Sayantan Nag Chowdhury, Srilena Kundu, Maja Duh, Matjaž Perc, Dibakar Ghosh, 2020, original scientific article

Abstract: Evolutionary game theory in the realm of network science appeals to a lot of research communities, as it constitutes a popular theoretical framework for studying the evolution of cooperation in social dilemmas. Recent research has shown that cooperation is markedly more resistant in interdependent networks, where traditional network reciprocity can be further enhanced due to various forms of interdependence between different network layers. However, the role of mobility in interdependent networks is yet to gain its well-deserved attention. Here we consider an interdependent network model, where individuals in each layer follow different evolutionary games, and where each player is considered as a mobile agent that can move locally inside its own layer to improve its fitness. Probabilistically, we also consider an imitation possibility from a neighbor on the other layer. We show that, by considering migration and stochastic imitation, further fascinating gateways to cooperation on interdependent networks can be observed. Notably, cooperation can be promoted on both layers, even if cooperation without interdependence would be improbable on one of the layers due to adverse conditions. Our results provide a rationale for engineering better social systems at the interface of networks and human decision making under testing dilemmas.
Keywords: cooperation, interdependent networks, mobile agents, prisoner's dilemma, snowdrift game, game theory, mobility, rational agents
Published in DKUM: 15.01.2025; Views: 0; Downloads: 5
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9.
Resonance graphs and a binary coding of perfect matchings of outerplane bipartite graphs
Simon Brezovnik, Niko Tratnik, Petra Žigert Pleteršek, 2023, original scientific article

Abstract: The aim of this paper is to investigate resonance graphs of $2$-connected outerplane bipartite graphs, which include various families of molecular graphs. Firstly, we present an algorithm for a binary coding of perfect matchings of these graphs. Further, $2$-connected outerplane bipartite graphs with isomorphic resonance graphs are considered. In particular, it is shown that if two $2$-connected outerplane bipartite graphs are evenly homeomorphic, then its resonance graphs are isomorphic. Moreover, we prove that for any $2$-connected outerplane bipartite graph $G$ there exists a catacondensed even ring systems $H$ such that the resonance graphs of $G$ and $H$ are isomorphic. We conclude with the characterization of $2$-connected outerplane bipartite graphs whose resonance graphs are daisy cubes.
Keywords: graph theory, resonance graphs, bipartite graphs
Published in DKUM: 10.12.2024; Views: 0; Downloads: 8
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10.
Immersive technology and hand hygiene : scoping review
Dominika Muršec, Sonja Šostar-Turk, Urška Rozman, Mateja Lorber, Nino Fijačko, Dominika Vrbnjak, 2024, review article

Abstract: Background The use of immersive technology in healthcare education is on the rise, yet its impact on learner engagement, knowledge retention, and specifically in areas like hand hygiene training, remains underexplored. The aim of this scoping review was to summarize the existing studies of immersive technology in hand hygiene training of healthcare providers and health professions students. Methods A scoping review following the Levac et al. framework was conducted. The literature search was performed in databases PubMed, CINAHL Ultimate, ScienceDirect (Elsevier), Web of Science in addition to Google Scholar and ProQuest Dissertation & Theses. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis: Extension for Scoping Reviews (PRIMSA-ScR) guideline was used to report the results. We analysed data using tabular and descriptive summary. Results In the final analysis 11 studies from seven countries were included. Most of the studies (n = 10, 90,91%) used virtual reality in hand hygiene training of healthcare providers and health professions students. Most studies have found that immersive technology is useful in teaching hand hygiene (n = 6, 54,55%). There are some theories and concepts that support the teaching of hand hygiene with immersive technology, but most of the research is not supported by them. Theories or concepts were included in two studies (18,18%). Conclusion Immersive technology, especially virtual reality, enhances hand hygiene learning and engagement compared to traditional methods. However, most studies lack theoretical support. To advance this field, exploring immersive technology for further research and incorporating relevant theories is encouraged. Additionally, conducting a thorough cost-effectiveness analysis and establishing a robust evaluation framework, encompassing both short-term and long-term outcomes, will be beneficial for a comprehensive understanding of the impact of immersive technology in hand hygiene education.
Keywords: immersive technology, hand hygiene, usefulness, theory, concept
Published in DKUM: 27.11.2024; Views: 0; Downloads: 7
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