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Organisational effectiveness and customer satisfaction
Milan Ambrož, Martina Praprotnik, 2008, original scientific article

Abstract: This paper presents a test of the relationship between organizational culture as a crucial indicator of organizational effectiveness and customer satisfaction using service-unit data from two health resorts. Ensuring survival of the service organisation in the long run requires adaptations which are oriented towards achieving maximum customer satisfaction. This study intended to unveil the effect organisational factors have on customer service orientation from the customer and employee point of view within a two health resort service setting. The finding suggests that when trying to predict the comparative degree which organisational effectiveness factors have in satisfying customers' needs, performance, adaptability and mission can be of the highest importance. Some effects like performance were uniform for employees and customers, while others varied depending on the organisation and the customer or employee group. Furthermore, findings suggest that service performance and organisation mission of the service organisation predict customer satisfaction based on established and proven health services. In this context there is no room for innovation, despite the fact that employees and customers do not share similar views about the impact of organisational effectiveness. Developing an effective service organisation can provide a competitive advantage to the organisation. Critical for the success of the service organisation is that organisational agents have a clear view of the existing organisation effectiveness and a clear view of the customer expectations in this area.
Keywords: organisational effectiveness, customer satisfaction, customer complexity, service orientation, survival, adaptability
Published: 04.12.2017; Views: 821; Downloads: 300
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3.
Survival of node-negative breast cancer patients treated at the University Medical Centre Maribor in the period 2000-2009
Nina Fokter Dovnik, Darja Arko, Nina Čas-Sikošek, Iztok Takač, 2017, original scientific article

Abstract: Introduction: Breast cancer is increasingly diagnosed in the early stages without regional nodal involvement. The aim of the present study was to determine the 5-year overall (OS) and breast cancer specific survival (BCSS) for patients with node-negative breast cancer treated at the University Medical Centre Maribor, and compare it with survival at the national level. Methods: Medical records were searched for information on patients with lymph node-negative invasive breast cancer who received primary treatment at the University Medical Centre Maribor in the period 2000–2009. Information on all Slovenian node-negative breast cancer patients diagnosed in the same period was obtained from the Cancer Registry of Republic of Slovenia. Time trends in survival were assessed by comparing the periods 2000–2004 and 2005–2009. Results: The 5-year OS and BCSS of patients treated in Maribor in the period 2000–2009 were 92.3% (95% CI, 90.5%– 94.1%) and 96.4% (95% CI, 95.2%–97.6%), respectively, and did not differ from the corresponding OS and BCSS for Slovenian patients. Although the improvement in OS for patients from Maribor diagnosed in the period 2005–2009 compared to 2000–2004 did not reach statistical significance (HR 0.73; 95% CI, 0.51–1.05; p=0.086), BCSS significantly improved over the same time periods (HR 0.53; 95% CI, 0.30–0.94; p=0.028). Conclusions: Survival of node-negative breast cancer patients treated at the University Medical Centre Maribor is comparable to survival of corresponding patients at the national level. The rising number of long-term breast cancer survivors places additional importance on survivorship care.
Keywords: breast cancer, survival, time trends, regional differences, Slovenia
Published: 26.06.2017; Views: 752; Downloads: 294
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4.
Prognostic significance of uPA/PAI-1 level, HER2 status, and traditional histologic factors for survival in node-negative breast cancer patients
Nina Fokter Dovnik, Iztok Takač, 2017, original scientific article

Abstract: Background: The association of HER2 status with urokinase plasminogen activator (uPA) and plasminogen activator inhibitor 1 (PAI-1) levels raises the question whether uPA/PAI-1 level carries additional clinically relevant prognostic information independently from HER2 status. The aim of our study was to compare the prognostic value of uPA/PAI-1 level, HER2 status, and traditional prognostic factors for survival in node-negative breast cancer patients. Patients and methods: A retrospective analysis of 858 node-negative breast cancer patients treated in Maribor University Clinical Center, Slovenia, in the years 2000-2009 was performed. Data were obtained from patient medical records. The median follow-up time was 100 months. Univariate and multivariate analyses of disease-free (DFS) and overall survival (OS) were performed using the Cox regression and the Cox proportional hazards model. Results: In univariate analysis, age, tumor size, grade, lymphovascular invasion, HER2 status and UPA/PAI-1 level were associated with DFS, and age, tumor size, grade, and uPA/PAI-1 level were associated with OS. In the multivariate model, the most important determinants of DFS were age, estrogen receptor status and uPA/PAI-1 level, and the most important factors for OS were patient age and tumor grade. The HR for death from any cause in the multivariate model was 1.98 (95% CI 0.83-4.76) for patients with high uPA and/or PAI-1 compared to patients with both values low. Conclusions: uPA/PAI-1 level clearly carries an independent prognostic value regardless of HER2 status in node-negative breast cancer and could be used in addition to HER2 and other markers to guide clinical decisions in this setting.
Keywords: node-negative breast cancer, adjuvant systemic treatment, survival, uPA/PAI-1, HER2 status
Published: 10.05.2017; Views: 726; Downloads: 324
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5.
Long-term survival in glioblastoma: methyl guanine methyl transferase (MGMT) promoter methylation as independent favourable prognostic factor
Uroš Smrdel, Mara Popović, Matjaž Zwitter, Emanuela Boštjančič, Andrej Zupan, Viljem Kovač, Damjan Glavač, Drago Bokal, Janja Jerebic, original scientific article

Abstract: Background: In spite of significant improvement after multi-modality treatment, prognosis of most patients with glioblastoma remains poor. Standard clinical prognostic factors (age, gender, extent of surgery and performance status) do not clearly predict long-term survival. The aim of this case-control study was to evaluate immuno-histochemical and genetic characteristics of the tumour as additional prognostic factors in glioblastoma. Patients and methods: Long-term survivor group were 40 patients with glioblastoma with survival longer than 30 months. Control group were 40 patients with shorter survival and matched to the long-term survivor group according to the clinical prognostic factors. All patients underwent multimodality treatment with surgery, postoperative conformal radiotherapy and temozolomide during and after radiotherapy. Biopsy samples were tested for the methylation of MGMT promoter (with methylation specific polymerase chain reaction), IDH1 (with immunohistochemistry), IDH2, CDKN2A and CDKN2B (with multiplex ligation-dependent probe amplification), and 1p and 19q mutations (with fluorescent in situ hybridization). Results: Methylation of MGMT promoter was found in 95% and in 36% in the long-term survivor and control groups, respectively (p < 0.001). IDH1 R132H mutated patients had a non-significant lower risk of dying from glioblastoma (p = 0.437), in comparison to patients without this mutation. Other mutations were rare, with no significant difference between the two groups. Conclusions: Molecular and genetic testing offers additional prognostic and predictive information for patients with glioblastoma. The most important finding of our analysis is that in the absence of MGMT promoter methylation, longterm survival is very rare. For patients without this mutation, alternative treatments should be explored.
Keywords: glioblastoma, long-term survival, methyl guanine methyl transferase, prognostic factor
Published: 05.04.2017; Views: 643; Downloads: 347
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6.
“SURVIVAL OF THE FITTEST” IN JACK LONDON’S THE CALL OF THE WILD
Simona Predanič, 2015, undergraduate thesis

Abstract: The subject of this graduation thesis is Jack London’s unconventional novel The Call of the Wild. The work falls into the genre of animal fiction, as the protagonist is a dog which possesses human attributes. The author’s philosophy of life is highly reflected in the book, as well as the influences of the survival philosophies of Charles Darwin and Herbert Spencer. The impact of Herbert Spencer’s “survival of the fittest” ethic on the author and its reflection in The Call of the Wild are the main focus of this study. To achieve this goal, historical research about the author’s biography, influences on his beliefs, survival theories of Herbert Spencer and Charles Darwin and facts about social Darwinism was conducted. Findings of the historical research were then used to conduct an analysis on the text. This investigation of the text showed that the “survival of the fittest” ethic does prevail throughout the work; however, Darwin’s ideas on sympathy are also reflected in some areas of the work, showing that the protagonist survives not merely because of his superior psycho-physical features but also because of the sympathy or affection expressed by other characters towards the protagonist.
Keywords: Jack London, canine protagonist, survival of the fittest, Herbert Spencer, Charles Darwin, sympathy, social Darwinism
Published: 01.06.2015; Views: 1072; Downloads: 71
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7.
Survival and expansion of Pistia stratiotes L. in a thermal stream in Slovenia
Nina Šajna, Maja Haler, Sonja Škornik, Mitja Kaligarič, 2007, original scientific article

Abstract: We report about successful winter survival of a tropical plant Pistia stratiotes in a natural thermal stream Topla in Slovenia in temperate climate zone in central Europe. Only 2 years after its first occurrence in 2001 P. stratiotes managed to cover most of the water body where the thermal springs cause an elevated temperature (>17 °C year round). Enhanced biomass production of this invasive species took place in spring and summer and new stolons were formed at the end of the vegetation season. Over the winter older rosettes decayed and only small rosettes survived besides new rosettes formed from stolons. Plants developed flowers in April through August. Observations in December revealed viable seed production and seed presence in the sediment.
Keywords: botany, water plants, tropical plant, thermal water, temperate zone, winter survival, plants trait
Published: 07.06.2012; Views: 1315; Downloads: 110
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