Search the digital library catalog

Abstract: Background and purpose: The aim of this study was to examine the risk factors, prodromal symptoms, non-motor symptoms (NMS), and motor symptoms (MS) in different Parkinson’s disease (PD) non-motor subtypes, classified using newly established criteria and a data-driven approach. Methods: A total of 168 patients with idiopathic PD underwent comprehensive NMS and MS examinations. NMS were assessed by the Non-Motor Symptom Scale (NMSS), Montreal Cognitive Assessment (MoCA), Hamilton Depression Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), REM Sleep Behavior Disorder Screening Questionnaire (RBDSQ), Epworth Sleepiness Scale (ESS), Starkstein Apathy Scale (SAS) and Fatigue Severity Scale (FSS). Motor subtypes were classified based on Stebbins’ method. Patients were classified into groups of three NMS subtypes (cortical, limbic, and brainstem) based on the newly designed inclusion criteria. Further, data-driven clustering was performed as an alternative, statistical learning-based classification approach. The two classification approaches were compared for consistency. Results: We identified 38 (22.6%) patients with the cortical subtype, 48 (28.6%) with the limbic, and 82 (48.8%) patients with the brainstem NMS PD subtype. Using a data-driven approach, we identified five different clusters. Three corresponded to the cortical, limbic, and brainstem subtypes, while the two additional clusters may have represented patients with early and advanced PD. Pearson chi-square test of independence revealed that a priori classification and cluster membership were significantly related to one another with a large effect size (χ2(8) = 175.001, p < 0.001, Cramer’s V = 0.722). The demographic and clinical profiles differed between NMS subtypes and clusters. Conclusion: Using the actuarial and clustering approach, marked differences between individual NMS subtypes were found. The newly established criteria have potential as a simplified tool for future clinical research of NMS subtypes of Parkinson’s disease.
Keywords: Parkinson’s disease, non-motor symptoms subtypes, a priori classification, cluster analysis
Published in DKUM: 07.04.2025; Views: 0; Downloads: 2
Full text (1,37 MB)
This document has many files! More...

Abstract: Naturally flows have been the scope of the scientific research for centuries, Rayleigh-Benard convection being one of the leading. Many researchers have considered the flow patterns, boundary conditions, various cavities, nanofluids, theoretically, numerically, and experimentally. The flow was investigated in atmosphere and in nanofluids, in air, water, molten metals, non-Newtonian fluids. Almost all research focuses on 2-D or 3-D analysis of flow in laterally unlimited enclosures, as parallel plates or coaxial cylinders. In technical practice, only limited enclosures exist. This paper presents numerical and real experimental results for the test chamber with ratio 4×2×1 in x-, y-, and z direction, respectfully. The measurements were taken at fifteen different positions on the faces of the tank. Probes used are PT100 elements. As the chamber is limited in all directions, the results have shown strong influence of the lateral walls. The results are compared with the those obtained by IR camera. Various fluids were tested, and results for motor oil will be presented.
Keywords: Rayleigh-Bénard convection, temperature profile, PT100 probe, motor oil, numerical simulation
Published in DKUM: 27.03.2025; Views: 0; Downloads: 1
Full text (3,41 MB)
This document has many files! More...

Abstract: V magistrskem delu je predstavljen proces načrtovanja in konstruiranja enoosnega pozicionerja za različne nosilnosti. Cilj je bil razviti pozicioner, ki izboljšuje funkcionalnost, stroškovno učinkovitost in prilagodljivost v primerjavi z obstoječimi rešitvami. Izbran je bil servo motor kot pogon in harmonični reduktor kot gonilo. Uporaba programa Autodesk Inventor Professional 2024 je omogočila izdelavo zvarjenega ohišja in celotnega sestava. Ekonomična analiza je potrdila smiselnost lastne izdelave. Narejeni so bili načrti za uporabljene polizdelke, načrt zvarjenca ohišja in načrt njegove obdelave. Delo zaključuje s sklepi in predlogi izboljšav, ko se izdela prototip.
Keywords: enoosni pozicioner, harmonično gonilo, servo motor, konstruiranje, ekonomična analiza
Published in DKUM: 03.03.2025; Views: 0; Downloads: 0
Full text (3,44 MB)

Keywords: electromyography, vibration, antagonist muscle, motor unit, vastus lateralis
Published in DKUM: 17.01.2025; Views: 0; Downloads: 4
Full text (1,41 MB)

Abstract: Proučevan je bil vpliv dodatka piroliznega olja, pridobljenega iz polietilena nizke gostote dizelskemu gorivu na pojavnost kavitacije v vbrizgalni šobi dizelskega motorja. V numerični simulaciji s programsko opremo Ansys Fluent so bile upoštevane lastnosti treh različnih goriv: čistega dizelskega goriva, dizelskega goriva z dodatkom 10% in 20% piroliznega olja (volumski deleži). Analiza rezultatov je pokazala, da dodajanje piroliznega olja dizelskemu gorivu vpliva na pojavnost kavitacije. Najnižja pojavnost kavitacije je bila zabeležena pri sto odstotnem dizelskem gorivu, najvišja pa pri gorivu z dodatkom 20% piroliznega olja. Pirolizno olje, pridobljeno iz polietilena nizke gostote ima nižji vrednosti viskoznosti in gostote kot dizelsko gorivo. Možno je sklepati, da nižji vrednosti viskoznosti in gostote vplivata na večjo pojavnost kavitacije pri gorivu z višjim volumskim deležem piroliznega olja iz polietilena nizke gostote v zmesi.
Keywords: kavitacija, računalniška dinamika tekočin, pirolizno olje, polietilen nizke gostote, vbrizgalna šoba, dizelski motor
Published in DKUM: 08.01.2025; Views: 0; Downloads: 28
Full text (2,94 MB)