1. Evidence-Based Recommendations for Dietary Supplementation During Pregnancy: Is It Time for a Product Recall?Leona Cilar Budler, Marija Spevan, Kata Ivanišević, Marko Budler, 2025, review article Abstract: Background
Micronutrient deficiencies in pregnant women are linked to serious health issues, including conception difficulties, spontaneous abortions, preterm births, low birth weight, birth defects and long-term metabolic disorders. Despite the recognized importance of dietary supplementation during pregnancy, rigorous research and supplementation monitoring remain limited.
Objective
This study aimed to review the evidence on the impact of dietary supplementation on maternal and infant outcomes and to provide evidence-based recommendations for dietary supplementation during pregnancy.
Methods
A systematic search, analysis, and synthesis of randomized controlled trials (RCTs) were conducted between October and January 2022. Databases searched included PubMed, CINAHL with Full Text, Google Scholar and CrossRef. The study adhered to PRISMA guidelines and applied inclusion and exclusion criteria to identify relevant studies. A total of 51 RCTs were included and assessed for quality, categorizing articles as moderate or high quality.
Results
Of the 51 RCTs analyzed, 47 (92.16%) were of moderate quality, and 4 (7.84%) were of high quality. Findings revealed that recommended dietary supplementation doses for pregnant women are often set well below safety thresholds. Evidence supporting the efficacy of certain vitamins and minerals in pregnancy remains inconclusive. The study highlighted a dose–response conundrum, with an emphasis on identifying effective and safe doses.
Conclusion
Micronutrient deficiencies in pregnant women pose significant risks to maternal and infant health. Current dietary supplementation recommendations require enhancement and alignment with the latest and most robust evidence. This study provides a comprehensive overview of state-of-the-art evidence and underscores the importance of bridging gaps in supplementation guidelines to optimize maternal and infant health outcomes. Keywords: EBN, pregnancy, vitamins, minerals, FDA, infant Published in DKUM: 27.01.2025; Views: 0; Downloads: 8
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2. The distribution of minerals in crucial plant parts of various elderberry (Sambucus spp.) interspecific hybridsNataša Imenšek, Vilma Sem, Mitja Kolar, Anton Ivančič, Janja Kristl, 2021, original scientific article Abstract: In view of growing requirements of the food industry regarding elderberries (genusSambucus), a need to increase their productivity and improve their chemical composition has emerged.With this purpose in mind, numerous elderberry interspecific hybrids have been created. In thepresent work, the content of minerals in their crucial plant parts was studied. It was also investigatedwhether superior genotypes regarding the mineral composition of berries and inflorescences could bepredicted at early stages of plant development. The results showed that elderberry leaves containedthe highest amounts of Ca, Mg, Mn, Zn, and Sr, while K and P were predominant in fruit stalks.Fe and Al prevailed in roots and Cu in bark. Although berries showed lower mineral contentcompared to other plant parts, their mineral content is not negligible and could be comparable toother commonly consumed berries. Genotypes with a favorable mineral content of inflorescencesand berries could be predicted on the basis of known mineral composition of their shoots and leaves.The study also indicates thatS. nigragenotypes and the majority of interspecific hybrids analyzedare suitable for further genetic breeding or cultivation. Keywords: interspecific hybrids, minerals, plant parts, elderberry, Sambucus Published in DKUM: 20.08.2024; Views: 70; Downloads: 9
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3. Strawberries from integrated and organic production : mineral contents and antioxidant activityJanja Kristl, Andreja Urbanek Krajnc, Branko Kramberger, Silva Grobelnik Mlakar, 2013, original scientific article Abstract: As the nutritional quality of food is becoming increasingly more important forconsumers, significant attention needs to be devoted to agricultural practices and their influences on the nutrient contents in food. The presentedinvestigation studied the mineral contents and antioxidant activitiesin the fruits of four organically-grown strawberry cultivars 'St. Pierre', 'Elsanta', 'Sugar Lia' and 'Thuchampion' when compared to those of integrated-grown plants. The strawberries were digested and analyzed for K, Mg, Fe, Zn, Cu, and Mn using an atomic absorption spectrometer, whilst P was analyzed using a vanadate-molybdate method. In addition, antioxidant activity was estimated by using the ABTS assay. The results showed that the mineral contents and antioxidant activities in strawberries depends on the cultivar, and its production system. Organically-grown fruits showed higher antioxidant activities and Cu content than the integrated fruits, whilst the integrated fruits were superior in their contents of P, K, Mg, Fe and Mn. All the cultivars showed similar Zn content, probably reflecting the fact that the Zn content in strawberries does not depend on the cultivar. Keywords: strawberries, minerals, antioxidant activity, production system Published in DKUM: 30.12.2015; Views: 1528; Downloads: 153
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