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Diabetic cardiomyopathy : an under-recognized cause of heart failure in diabetic patients
David Šuran, Vojko Kanič, Andreja Sinkovič, 2020, review article

Keywords: left ventricular diastolic dysfunction
Published in DKUM: 23.01.2023; Views: 43; Downloads: 4
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Uravnavanje temperature z ezofagealno hladilno sondo pri pacientih po oživljanju
Jernej Mori, 2019, master's thesis

Abstract: S terapevtsko hipotermijo oziroma ciljnim uravnavanjem telesne temperature skušamo pri pacientih po srčnem zastoju preprečiti ishemično možgansko okvaro in tako posledično vplivati na kvaliteto življenja po srčnem zastoju. Namen raziskave je bil ugotoviti učinkovitost uravnavanja telesne temperature z ezofagealno hladilno sondo v primerjavi z drugimi načini ohlajanja pacienta po uspešnem oživljanju.
Keywords: Srčni zastoj, terapevtska hipotermija, načini ohlajanja pacienta, enota intenzivne terapije, medicinska sestra.
Published in DKUM: 13.01.2020; Views: 1167; Downloads: 309
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Pojav akutne ledvične odpovedi pri bolnikih z akutnim miokardnim infarktom z dvigom veznice ST
Klara Masnik, Matic Mihevc, 2017, final research report

Published in DKUM: 23.07.2018; Views: 1157; Downloads: 58
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Efficacy of a bundle approach in preventing the incidence of ventilator associated pneumonia (VAP)
Sandra Burja, Tina Belec, Nika Bizjak, Jernej Mori, Andrej Markota, Andreja Sinkovič, 2017, original scientific article

Abstract: Ventilator-associated pneumonia (VAP) is a potentially preventable iatrogenic illness that may develop following mechanical ventilation. A bundle for the prevention of VAP consists of different measures which may vary between institutions, and may include: elevation of the head of the bed, oral care with chlorhexidine, subglottic suctioning, daily assessment for extubation and the need for proton-pump inhibitors, use of closed suction systems, and maintaining endotracheal cuff pressure at 25 cmH2O. Our aim was to determine the efficacy of a VAP prevention bundle, consisting of the above-mentioned measures, by evaluating the incidence of VAP before (no-VAP-B group) and after (VAP-B group) the introduction of the bundle. We retrospectively evaluated the data for patients who were mechanically ventilated with an endotracheal tube, in the period between 1 September and 31 December 2014 (no-VAP-B group, n = 55, 54.5% males, mean age 67.8 ± 14.5 years) and between 1 January to 30 April 2015 (VAP-B group, n = 74, 62.1% males, mean age 64.8 ± 13.7 years). There were no statistically significant differences between no-VAP-B and VAP-B groups in demographic data, intensive care unit (ICU) mortality, hospital mortality, duration of ICU treatment, and duration of mechanical ventilation. No significant differences in the rates of VAP and early VAP (onset ≤7 days after intubation) were found between no-VAP-B and VAP-B groups (41.8% versus 25.7%, p = 0.06 and 10.9% versus 12.2%, p > 0.99, respectively). However, a significant decrease in the late VAP (onset >8 days after intubation) was found in VAP-B group compared to no-VAP-B group (13.5% versus 30.9%, p = 0.027). Overall, our results support the use of VAP prevention bundle in clinical practice.
Keywords: ventilator-associated pneumonia, VAP, primary prevention, epidemiology, medical devices, intratracheal intubation, bundle
Published in DKUM: 13.11.2017; Views: 1312; Downloads: 342
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Optimization of induction of mild therapeutic hypothermia with cold saline infusion : a laboratory experiment
Jure Fluher, Andrej Markota, Andraž Stožer, Andreja Sinkovič, 2015, original scientific article

Abstract: Cold fluid infusions can be used to induce mild therapeutic hypothermia after cardiac arrest. Fluid temperature higher than 4°C can increase the volume of fluid needed, prolong the induction phase of hypothermia and thus contribute to complications. We performed a laboratory experiment with two objectives. The first objective was to analyze the effect of wrapping fluid bags in ice packs on the increase of fluid temperature with time in bags exposed to ambient conditions. The second objective was to quantify the effect of insulating venous tubing and adjusting flow rate on fluid temperature increase from bag to the level of an intravenous cannula during a simulated infusion. The temperature of fluid in bags wrapped in ice packs was significantly lower compared to controls at all time points during the 120 minutes observation. The temperature increase from the bag to the level of intravenous cannula was significantly lower for insulated tubing at all infusion rates (median temperature differences between bag and intravenous cannula were: 8.9, 4.8, 4.0, and 3.1°C, for non-insulated and 5.9, 3.05, 1.1, and 0.3°C, for insulated tubing, at infusion rates 10, 30, 60, and 100 mL/minute, respectively). The results from this study could potentially be used to decrease the volume of fluid infused when inducing mild hypothermia with an infusion of cold fluids.
Keywords: cardiac arrest, intravenous infusion, therapeutic hypothermia
Published in DKUM: 03.08.2017; Views: 863; Downloads: 135
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