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Abstract: Background Chronic non-communicable diseases are the world’s leading cause of death and disability. The emerging field of lifestyle medicine requires equipping healthcare professionals with instruments, knowledge, skills and competencies. Measuring an individual’s lifestyle with a valid and reliable instrument is the first step in promoting it. The aim of the study was to validate the Slovenian adaptation of the Healthy Lifestyle and Personal Control Questionnaire (HLPCQ). Methods A cross-sectional study was conducted among 666 questionnaire participants, and they were adult participants (aged 18 and above) from family medicine practices with cardiovascular diseases (CVDs) risk factors (e.g., hypertension, high cholesterol) but without a diagnosis of acute CVDs. The questionnaire included demographic data and anthropological measures and a translated English HLPCQ questionnaire. The instrument was translated using the forward-backwards translation method. The study was conducted in accordance with the principles of the World Medical Association Declaration of Helsinki. In addition to assessing the construct validity of the questionnaire, exploratory and confirmatory factor analyses were used to determine content and face validity, and internal consistency reliability. Results The mean age of male participants was 41.34 (± 13.220) years, the mean age of female participants was 40.31 (± 11.905) years. The Cronbach’s alpha was 0.852, and all questionnaire subscales had positive correlations. Sampling adequacy was confirmed by the Kaiser-Meyer-Olkin (KMO) index (0.851), and Bartlett’s test of sphericity was significant (χ² = 4647.694, p < 0.001), indicating suitability for Principal Component Analysis (PCA). PCA revealed a fivefactor solution, accounting for 50.67% of the total variance. Conclusions The most influential factors for a healthy lifestyle were daily routine, healthy dietary choices, avoidance of harmful dietary habits, organized physical activity, and social and mental balance. The Slovenian version had high factor validity and reliability. It can be used in Slovenian Community Health Centre to assess an individual’s control over various lifestyle dimensions. The instrument also holds potential for use in public health initiatives, supporting early identification of lifestyle-related risk factors and promoting preventive care strategies in the primary care setting.
Keywords: lifestyle, health behaviour, validity, public health, questionnaire, HLPCQ
Published in DKUM: 16.05.2025; Views: 0; Downloads: 0
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Abstract: This paper reviews benchmarking methods for evaluating large language models (LLMs) in healthcare settings. It highlights the importance of rigorous benchmarking to ensure LLMs' safety, accuracy, and effectiveness in clinical applications. The review also discusses the challenges of developing standardized benchmarks and metrics tailored to healthcare-specific tasks such as medical text generation, disease diagnosis, and patient management. Ethical considerations, including privacy, data security, and bias, are also addressed, underscoring the need for multidisciplinary collaboration to establish robust benchmarking frameworks that facilitate LLMs' reliable and ethical use in healthcare. Evaluation of LLMs remains challenging due to the lack of standardized healthcare-specific benchmarks and comprehensive datasets. Key concerns include patient safety, data privacy, model bias, and better explainability, all of which impact the overall trustworthiness of LLMs in clinical settings.
Keywords: artificial intelligence, benchmarking, chatbots, healthcare, large language models, natural language processing
Published in DKUM: 12.05.2025; Views: 0; Downloads: 0
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Abstract: Zaključno delo predstavlja primerjalno analizo funkcionalnosti in zmogljivosti štirih orodij za rudarjenje procesov. Raziskava temelji na večdimenzionalni oceni šestih ključnih sklopov funkcionalnosti. Rezultati kažejo, da odprtokodna orodja zagotavljajo visoko prilagodljivost in dostop do širokega nabora algoritmov, vendar zahtevajo obsežnejše tehnično znanje. Komercialna orodja nudijo intuitivne uporabniške vmesnike in napredne integracijske možnosti. Glavna ugotovitev raziskave je, da izbira najustreznejšega orodja temelji na specifičnih potrebah in tehničnih zmogljivostih organizacije.
Keywords: rudarjenje procesov, primerjalna analiza, poslovni procesi
Published in DKUM: 08.05.2025; Views: 0; Downloads: 8
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Abstract: Uporaba različnih adsorpcijskih sredstev za sušenje komprimiranega zraka je ključnega pomena v številnih industrijskih panogah, saj zagotavlja stabilne pogoje za delovanje opreme in preprečuje korozijo. V magistrskem delu smo proučevali razvoj granulirane aktivirane glinice, namenjene uporabi v sušilnikih komprimiranega zraka. Cilj je bil proizvesti granulat iz aluminijevega hidrata, aktivirane glinice in psevdoboehmita v različnih razmerjih, z namenom doseganja čim višje trdote granul, specifične površine 300 m²/g, določene po BET metodi, in kapacitete vodne adsorpcije (SWA) 15 %. V raziskavi smo uporabili dve različni vrsti glinice in tri tipe hidratov, da bi proučili njihov vpliv na lastnosti granulata. Poleg vpliva surovin smo proučevali še vpliv kalcinacije pri različnih temperaturah. Rezultati so pokazali, da delež aluminijevega hidrata pomembno vpliva na trdoto granul. Nižji deleži hidrata so omogočili izdelavo trdnejših granul zaradi manjše poroznosti, medtem ko je dodatek psevdoboehmita izboljšal trdoto, specifično površino in adsorpcijske lastnosti. Najboljši rezultati so bili doseženi pri formulaciji s 35 % hidrata, kjer so granule dosegle najvišjo trdoto 51 N in SWA 13,3 %, kar se približuje zastavljenim ciljem, ter z 20 % hidrata, kjer je bila dosežena najvišja specifična površina, ki je znašala 283,05 m2/g. Optimizacija je pokazala, da kalcinacija pri temperaturah nad 400 °C ni smiselna, saj ne prinaša bistvenih izboljšav in povečuje energetske stroške. Opravljene so bile tudi XRD analize za boljši vpogled v strukturno sestavo končnih produktov. Ugotovljena sta bila prevlada amorfnih faz pri nižjih temperaturah in prehod v χ ter κ glinico pri višjih temperaturah. Čeprav cilji niso bili povsem doseženi, raziskava predstavlja pomemben vpogled v vpliv surovin in procesnih parametrov na lastnosti granulata. Naše ugotovitve ponujajo trdno osnovo za nadaljnje raziskave in izboljšave materialov za doseganje konkurenčnosti na trgu.
Keywords: aktivirana glinica, aluminijev hidrat, adsorbent, granuliranje, adsorpcija
Published in DKUM: 06.05.2025; Views: 0; Downloads: 0
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Abstract: Pesticide use remains a problem in agriculture, contaminating natural ecosystems and affecting bees. Fungicides have been widely used worldwide, and honey bees can bring contaminated pollen and nectar to the colony, exposing the larvae. Studies on larval exposure to fungicides are still rare. Therefore, this work aimed to evaluate the effects of larval exposure to the fungicide picoxystrobin on biological parameters and cellular stress in the fat body. The larvae were single exposure on the fourth day (D4) to picoxystrobin at concentrations of 5 ng a.i./μL (PCX5), 45 ng a.i./μL (PCX45), 135 ng a.i./μL (PCX135), and 400 ng a.i./μL (PCX400). The effects on larval and pupal mortality, pupation rate, and emergence were evaluated. Additionally, cellular stress in the fat body was assessed in newly emerged bees. Exposure to PCX400 increased larval mortality by 26% and reduced the emergence of adult bees. The other concentrations did not affect larval and pupal mortality, or pupation and emergence rates. A cytotoxicity effect was observed in newly emerged bees from PCX400, indicated by positive immunolabeling of HSP70. Thus, a single exposure to picoxystrobin can impair larval development, induce a cellular stress response, and may interfere with colony dynamics.
Keywords: development, honey bee, non-target organism, strobilurin, toxicity
Published in DKUM: 23.04.2025; Views: 0; Downloads: 0
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