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Naslov:L-arginine intake effect on adenin nucleotide metabolism in rat parenchymal and reproductive tissues
Avtorji:ID Kocić, Gordana (Avtor)
ID Nikolić, J. (Avtor)
ID Jevtović, Tatjana (Avtor)
ID Sokolović, Dušan (Avtor)
ID Kocić, H. (Avtor)
ID Cvetković, T. (Avtor)
ID Pavlović, Miloš (Avtor)
ID Cencič, Avrelija (Avtor)
ID Stojanovic, D. (Avtor)
Datoteke:.pdf The_Scientific_World_Journal_2012_Kocic_et_al._L-Arginine_Intake_Effect_on_Adenine_Nucleotide_Metabolism_in_Rat_Parenchymal_and_Reproduc.pdf (1,16 MB)
MD5: 5C89A1EBD310A88C6FFE706E7145EFFC
 
URL http://www.hindawi.com/journals/tswj/2012/208239/
 
Jezik:Angleški jezik
Vrsta gradiva:Znanstveno delo
Tipologija:1.01 - Izvirni znanstveni članek
Organizacija:MF - Medicinska fakulteta
Opis:L-arginine is conditionally essential amino acid, required for normal cell growth, protein synthesis, ammonia detoxification, tissue growth and general performance, proposed in the treatment of men sterility and prevention of male impotence. The aim of the present paper was to estimate the activity of the enzymes of adenine nucleotide metabolismČ 5' -nucleotidase ( 5'-NU), adenosine deaminase (ADA), AMP deaminase, and xanthine oxidase (XO), during dietary intake of L-arginine for a period of four weeks of male Wistar rats. Adenosine concentration in tissues is maintained by the relative activities of the adenosine-producing enzyme, 5' -NU and the adenosine-degrading enzyme-ADA adenosine deaminase. Dietary L-arginine intake directed adenine nucleotide metabolism in liver, kidney, and testis tissue toward the activation of adenosine production, by increased 5' -NU activity and decreased ADA activity. Stimulation of adenosine accumulation could be of importance in mediating arginine antiatherosclerotic, vasoactive, immunomodulatory, and antioxidant effects. Assuming that the XO activity reflects the rate of purine catabolism in the cell, while the activity of AMP deaminase is of importance in ATP regeneration, reduced activity of XO, together with the increased AMP-deaminase activity, may suggest that adenine nucleotides are presumably directed to the ATP regenerating process during dietary L-arginine intake.
Ključne besede:biochemistry
Status publikacije:Objavljeno
Verzija publikacije:Objavljena publikacija
Leto izida:2012
Št. strani:str. 1-4
Številčenje:Letn. 2012
PID:20.500.12556/DKUM-66223 Novo okno
ISSN:1537-744X
UDK:577
COBISS.SI-ID:3355948 Novo okno
DOI:10.1100/2012/208239 Novo okno
ISSN pri članku:1537-744X
NUK URN:URN:SI:UM:DK:TUR5EPGM
Datum objave v DKUM:15.06.2017
Število ogledov:1035
Število prenosov:152
Metapodatki:XML DC-XML DC-RDF
Področja:Ostalo
:
KOCIĆ, Gordana, NIKOLIĆ, J., JEVTOVIĆ, Tatjana, SOKOLOVIĆ, Dušan, KOCIĆ, H., CVETKOVIĆ, T., PAVLOVIĆ, Miloš, CENCIČ, Avrelija in STOJANOVIC, D., 2012, L-arginine intake effect on adenin nucleotide metabolism in rat parenchymal and reproductive tissues. The Scientific World Journal [na spletu]. 2012. Vol. 2012, p. 1–4. [Dostopano 6 april 2025]. DOI 10.1100/2012/208239. Pridobljeno s: https://dk.um.si/IzpisGradiva.php?lang=slv&id=66223
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Gradivo je del revije

Naslov:The Scientific World Journal
Založnik:Hindawi Publishing Corporation
ISSN:1537-744X
COBISS.SI-ID:2607642 Novo okno

Licence

Licenca:CC BY 4.0, Creative Commons Priznanje avtorstva 4.0 Mednarodna
Povezava:http://creativecommons.org/licenses/by/4.0/deed.sl
Opis:To je standardna licenca Creative Commons, ki daje uporabnikom največ možnosti za nadaljnjo uporabo dela, pri čemer morajo navesti avtorja.
Začetek licenciranja:15.06.2017

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Jezik:Slovenski jezik
Ključne besede:biokemija


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